Results 131 to 140 of about 2,464,663 (310)

Fast free-form deformation using graphics processing units

, 2010
A large number of algorithms have been developed to perform non-rigid registration and it is a tool commonly used in medical image analysis. The Free-Form Deformation algorithm is a well-established technique, but is extremely time consuming.
Ridgway, G.R., Taylor, Z.A., Hawkes, D.J., Fox, Nick C., Barnes, Josephine, Modat, M., Fox, N.C., Taylor, Zeike A,, Ourselin, Sebastien, Modat, Marc, Barnes, J., Ourselin, S., Lehmann, Manja, Lehmann, M., Ridgway, Gerard R., Hawkes, David J.   +15 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Estimating total cross sections from neutron-nucleus collisions using a simple functional form

, 2006
Total cross sections for neutron scattering from nuclei, with energies ranging from 10 to 600 MeV and from many nuclei spanning the mass range 6Li to 238U, have been analyzed using a simple, three-parameter, functional form. The calculated cross sections
Karataglidis, Steven, Amos, Ken, Deb, Pradip   +2 more
core  

Seaweed functional strategies, functional groups, and taxon dynamics through a 213-year historical series of Rio De Janeiro Bay

Scientific Reports
From Darwin’s visit to nowadays, we analyzed the changes in species- and genus-level richness and turnover, equity, diversity, composition, as well as functional group and functional strategy dynamics over a 213-year historical series of the seaweed ...
João P. G. Machado, Vinícius P. Oliveira   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Diet, immunity and functional foods

, 2007
Functional foods (specific nutrient and/or food components) should beneficially affect one or more target functions in the body. The use of functional foods as a form of preventive medicine has been the subject of much research over the last two decades.
Hoyles, L., Vulevic, J.
core   +1 more source

Continuous endosomes form functional subdomains and orchestrate rapid membrane trafficking in trypanosomes

eLife
Endocytosis is a common process observed in most eukaryotic cells, although its complexity varies among different organisms. In Trypanosoma brucei, the endocytic machinery is under special selective pressure because rapid membrane recycling is essential ...
Fabian Link, Alyssa Borges, Oliver Karo, Marvin Jungblut, Thomas Müller, Elisabeth Meyer-Natus, Timothy Krüger, Stefan Sachs, Nicola G Jones, Mary Morphew, Markus Sauer, Christian Stigloher, J Richard McIntosh, Markus Engstler   +13 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

BOX-COX TRANSFORMATIONS AND ERROR TERM SPECIFICATION IN DEMAND MODELS

This paper analyzes the influence of error-term specification and functional form on a quarterly demand model for beef. The Box-Cox transformation is used to generalize the functional form while the equation error term is postulated to be both ...
Blaylock, James R., Smallwood, David M.
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source