Results 161 to 170 of about 107,051 (305)

Monitoring and regulatory role of the balanced scorecard in controlling organisational identities

, 2010
This thesis employs the theoretical fusion of disciplinary knowledge, interlacing an analysis from both functional and interpretive frameworks and applies these paradigms to three concepts—organisational identity, the balanced scorecard performance ...
Kim, Jungsun
core  

Single cell map of the adult female mouse urethra reveals epithelial and stromal macrophages with distinct functional identities. [PDF]

Mucosal Immunol
Jasmine, Samtiya M, Rodrigues R, Mandal A, Kavya TT, Anushree A, Lafin JT, Vezina CM, Strand DW, Binoy Joseph D.   +9 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Occupational Therapists: A Study of Managing Multiple Identities

, 2010
This qualitative study uncovered the identity construction of occupational therapists located in two regions of the United States. In utilizing an organizational communication studies lens, it was discovered that occupational therapists possess multiple,
Lloyd, Katherine Elise
core  

Spatially separated epithelium-associated and lamina propria neutrophils present distinct functional identities in the inflamed colon mucosa. [PDF]

Mucosal Immunol
Yalom LK, Herrnreiter CJ, Bui TM, Lockhart J, Piccolo EB, Ren X, Wei C, Serdiukova A, Thorp EB, Dulai PS, Sumagin R.   +10 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Weighted Popoviciu type inequalities via generalized Montgomery identities

, 2015
We obtained useful identities via generalized Montgomery identities, by which the inequality of Popoviciu for convex functions is generalized for higher order convex functions. We investigate the bounds for the identities related to the generalization of
Butt, Saad Ihsan, Saad Ihsan Butt, Pečarić, Josip, Josip Pečarić   +3 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Topological Structure of Epigenetic Forests in Flower Morphogenesis. [PDF]

Bull Math Biol
Cortés-Poza Y, Pérez-Buendía JR.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source