Results 91 to 100 of about 406,386 (293)

The Technique of Measures of Noncompactness in Banach Algebras and Its Applications to Integral Equations

Abstract and Applied Analysis, 2013
We study the solvability of some nonlinear functional integral equations in the Banach algebra of real functions defined, continuous, and bounded on the real half axis.
Józef Banaś, Szymon Dudek
doaj   +1 more source

Riccati equation‐based generalization of Dawson's integral function [PDF]

Mathematical Methods in the Applied Sciences, 2007
AbstractA new generalization of Dawson's integral function based on the link between a Riccati nonlinear differential equation and a second‐order ordinary differential equation is reported. The MacLaurin expansion of this generalized function is built up and to this end an explicit formula for a generic cofactor of a triangular matrix is deduced ...
MESSINA, Riccardo, JIVULESCU, Maria Anastasia, MESSINA, Antonino, NAPOLI, Anna   +3 more
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Solvability of nonlinear integral equations of product type

Electronic Journal of Differential Equations, 2018
This article concerns nonlinear functional integral equations of product type. The first two equations set on a the positive half-axis encompass different classes of nonlinear integral equations and may involve the product of finitely many integral ...
Bilal Boulfoul, Azzeddine Bellour, Smail Djebali   +2 more
doaj  

Zero-sum linear quadratic stochastic integral games and BSVIEs [PDF]

, 2010
This paper formulates and studies a linear quadratic (LQ for short) game problem governed by linear stochastic Volterra integral equation. Sufficient and necessary condition of the existence of saddle points for this problem are derived. As a consequence
Shi, Yufeng, Wang, Tianxiao
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Form factors at strong coupling via a Y-system

, 2010
We compute form factors in planar N=4 Super Yang-Mills at strong coupling. Namely we consider the overlap between an operator insertion and 2n gluons. Through the gauge/string duality these are given by minimal surfaces in AdS space.
A Brandhuber, AB Zamolodchikov, AB Zamolodchikov, AB Zamolodchikov, Alexander Zhiboedov, AN Kirillov, AR Steif, BM McCoy, C Anastasiou, C-N Yang, D Gaiotto, DM Hofman, GP Korchemsky, HJ Vega De, J Polchinski, JM Drummond, Juan Maldacena, K Pohlmeyer, LF Alday, LF Alday, LF Alday, LF Alday, M Bañados, N Dorey, NJ Hitchin, P Fendley, SL Lukyanov, SS Gubser, V Duca Del, VA Kazakov, WL Neerven van, Z Bern   +31 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source