Results 81 to 90 of about 406,386 (293)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

$C^n$-almost periodic and almost periodic solutions for some nonlinear integral equations

Electronic Journal of Qualitative Theory of Differential Equations, 2012
In this paper, we investigate the existence of $C^n$-almost periodic solution for a class of nonlinear Fredholm integral equations, and the existence of almost periodic solution for a class of nonlinear functional integral equations.
Huisheng Ding, Yuan-Yuan Chen, Gaston N'Guérékata   +2 more
doaj   +1 more source

Integral equations involving generalized Mittag-Leffler function

Ukrains’kyi Matematychnyi Zhurnal, 2020
UDC 517.5 The paper deals with solving the integral equation with a generalized Mittag-Leffler function E α , β γ , q ( z ) that defines a kernel using a fractional integral operator. The existence of the solution is justified and necessary conditions on the integral equation admiting a solution are ...
Rachana Desai, I. A. Salehbhai, A. K. Shukla   +2 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Existence results for semilinear perturbed functional differential equations with nondensely defined operators

Fixed Point Theory and Applications, 2006
We will establish sufficient conditions for the existence of integral solutions and extremal integral solutions for semilinear functional differential equations with nondensely defined operators in Banach spaces.
S. K. Ntouyas, M. Benchohra, M. Belmekki   +2 more
doaj   +2 more sources

Solvability of m-product mixed non-linear functional integral equations

Beni-Suef University Journal of Basic and Applied Sciences
The purpose of this paper is devoted to establishing the existence of solutions for m-product non-linear functional integral equations with weakly singular and Riemann–Liouville integral terms.
Amar Deep, Manochehr Kazemi, Mohammad Ali Fariborzi Araghi, Mohammad Esmael Samei   +3 more
doaj   +1 more source

Comment on “Existence Theorem for Integral and Functional Integral Equations with Discontinuous Kernels”

Abstract and Applied Analysis, 2015
We present a counterexample to the main result of the abovementioned paper showing that this result is false and cannot be improved in a simple way.
Krzysztof A. Topolski
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Optimized Effective Potential Method in Current-Spin Density Functional Theory

, 2006
Current-spin density functional theory (CSDFT) provides a framework to describe interacting many-electron systems in a magnetic field which couples to both spin- and orbital-degrees of freedom.
E. Engel, E. K. U. Gross, E. Orestes, N. Helbig, S. Kurth, S. Pittalis, T. Grabo, T. Kreibich   +7 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source