Results 141 to 150 of about 2,198,997 (290)

Structural and functional integration of human forebrain organoids with the injured adult rat visual system. [PDF]

Cell Stem Cell, 2023
Jgamadze D, Lim JT, Zhang Z, Harary PM, Germi J, Mensah-Brown K, Adam CD, Mirzakhalili E, Singh S, Gu JB, Blue R, Dedhia M, Fu M, Jacob F, Qian X, Gagnon K, Sergison M, Fruchet O, Rahaman I, Wang H, Xu F, Xiao R, Contreras D, Wolf JA, Song H, Ming GL, Chen HI.   +26 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Gabrb3 is required for the functional integration of pyramidal neuron subtypes in the somatosensory cortex. [PDF]

Neuron, 2023
Babij R, Ferrer C, Donatelle A, Wacks S, Buch AM, Niemeyer JE, Ma H, Duan ZRS, Fetcho RN, Che A, Otsuka T, Schwartz TH, Huang BS, Liston C, De Marco García NV.   +14 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Eco-friendly high-throughput screening of cephalosporins impurities: Utilizing 2D-carbon microfiber fractionation system combined with quadrupole time of flight high-resolution mass spectrometer

Journal of Pharmaceutical Analysis
Lei Yang, Yan Wang, Zhao Wang, Meiyu Cui, Ruolan Jin, Hai-Bo Shang, Donghao Li   +6 more
doaj   +1 more source

Increased functional integration of emotional control network across the adult lifespan. [PDF]

Aging Brain
Bätz LR, Ye S, Schubbert M, Lan X, Ziaei M.   +4 more
europepmc   +1 more source

Functional Integration and Segregation in a Multilayer Network Model of Patients with Schizophrenia. [PDF]

Brain Sci, 2022
Wei J, Wang X, Cui X, Wang B, Xue J, Niu Y, Wang Q, Osmani A, Xiang J.   +8 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Functional Integration of Different-Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis. [PDF]

Adv Biol (Weinh)
Pfau DR, Rionda MA, Cho E, Clark JG, Kruger RE, Chan-Sui RK, Padmanabhan V, Moravek MB, Shikanov A.   +8 more
europepmc   +1 more source

GRM2 Regulates Functional Integration of Adult-Born DGCs by Paradoxically Modulating MEK/ERK1/2 Pathway. [PDF]

J Neurosci, 2023
Ma J, Hu Z, Yue H, Luo Y, Wang C, Wu X, Gu Y, Wang L.   +7 more
europepmc   +1 more source