Results 161 to 170 of about 2,198,997 (290)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Micro Biomimetic Eyeball for Humanoid Robots: A Visual System with High-Density Functional Integration Based on an Origami Mechanism. [PDF]

Adv Sci (Weinh)
Pu J, Chen Y, Wu Y, Yin C, Qu C, Xiao D, Wu X.   +6 more
europepmc   +1 more source

Editorial: Multilevel Organization and Functional Integration in Organisms. [PDF]

Front Physiol, 2021
Roux E, Marhl M, Mossio M.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Rethinking Dispersion in Nanotechnology: Biopolymer Nanostructures as Green Enablers of Functional Integration. [PDF]

Chempluschem
González-Domínguez JM.
europepmc   +1 more source

Editorial: A Novel Perspective for Photosystem I: An Emerging Hub for the Functional Integration of Photosynthesis and Metabolism. [PDF]

Front Plant Sci, 2022
Blanco NE, Gollan PJ, Mengin V, Nikkanen L, Fusari CM.   +4 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

High-Entropy Oxide Memristors for Neuromorphic Computing: From Material Engineering to Functional Integration. [PDF]

Nanomicro Lett
Yang JL, Tang XG, Gu X, Sun QJ, Tang ZH, Li WH, Jiang YP.   +6 more
europepmc   +1 more source

Functional integration of eye tissues and refractive eye development: Mechanisms and pathways. [PDF]

Exp Eye Res, 2021
Summers JA, Schaeffel F, Marcos S, Wu H, Tkatchenko AV.   +4 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source