Results 71 to 80 of about 37,182 (262)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Functional Reach Test between Dominant and Non Dominant Leg: A Cross-sectional Study

Journal of Clinical and Diagnostic Research
Introduction: Elderly individuals with balance disorders are vulnerable to falls. To prevent such events, it is imperative to evaluate and recognise the underlying causes of balance-associated issues.
Danah Mohammed Alyahya
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Objective assessment of tinnitus laterality.

PLoS ONE
Tinnitus is a condition which involves hearing sounds not present externally. This common condition can lead to a range of symptoms, including depression, resulting in a severe impact on quality of life.
Mehrnaz Shoushtarian, Jamal Esmaelpoor, Michelle M G Bravo, James B Fallon   +3 more
doaj   +1 more source

Functional study of DAND5 variant in patients with Congenital Heart Disease and laterality defects

BMC Medical Genetics, 2017
Background Perturbations on the Left-Right axis establishment lead to laterality defects, with frequently associated Congenital Heart Diseases (CHDs). Indeed, in the last decade, it has been reported that the etiology of isolated cases of CHDs or cases ...
Fernando Cristo, José M. Inácio, Salomé de Almeida, Patrícia Mendes, Duarte Saraiva Martins, José Maio, Rui Anjos, José A. Belo   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

CORTICAL ASYMMETRIES DURING HAND LATERALITY TASK VARY WITH HAND LATERALITY: A FMRI STUDY IN 295 PARTICIPANTS.

Frontiers in Human Neuroscience, 2016
The aim of this study was to characterize, using fMRI, the functional asymmetries of Hand Laterality Task (HLT) in a sample of 295 participants balanced for handedness.
Emmanuel Mellet, Bernard Mazoyer, Gaelle Leroux, Marc Joliot, Nathalie Tzourio-Mazoyer   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Altered functional connectivity differs in stroke survivors with impaired touch sensation following left and right hemisphere lesions

NeuroImage: Clinical, 2018
One in two survivors experience impairment in touch sensation after stroke. The nature of this impairment is likely associated with changes associated with the functional somatosensory network of the brain; however few studies have examined this.
Peter Goodin, Gemma Lamp, Rishma Vidyasagar, David McArdle, Rüdiger J. Seitz, Leeanne M. Carey   +5 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source