Results 41 to 50 of about 732,216 (305)

Central Executive Dysfunction and Deferred Prefrontal Processing in Veterans with Gulf War Illness. [PDF]

open access: yes, 2013
Gulf War Illness is associated with toxic exposure to cholinergic disruptive chemicals. The cholinergic system has been shown to mediate the central executive of working memory (WM).
Bennett, Ilana J   +7 more
core   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

MRI-guided cell membrane-camouflaged bimetallic coordination nanoplatform for combined tumor phototherapy

open access: yesMaterials Today Bio
Nanotechnology for tumor diagnosis and optical therapy has attracted widespread interest due to its low toxicity and convenience but is severely limited due to uncontrollable tumor targeting.
Mengyang Zhou   +7 more
doaj   +1 more source

Neuroimaging techniques in epilepsy [PDF]

open access: yes, 2010
Objective: To review state-of-the-art neuroimaging modalities in epilepsy and their clinical applications. Data sources and study selection: PubMed literature searches to March 2010, using the following key words: 'epilepsy', 'positron emission ...
Ho, WY   +4 more
core  

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

Switchable ROS generator and scavenger to prevent the cisplatin induced acute kidney injury and improve efficacy via synergistic chemodynamic/immune therapy

open access: yesMaterials Today Bio
Acute kidney injury (AKI) induced by cisplatin (DDP), which is accompanied with the generation of reactive oxygen species (ROS), is a severe side effect during treatment and restricts the application of DDP.
Yanan Ren   +10 more
doaj   +1 more source

Variation in the oxytocin receptor gene is associated with behavioral and neural correlates of empathic accuracy

open access: yesFrontiers in Behavioral Neuroscience, 2014
The neuromodulators oxytocin and serotonin have been implicated in regulating affective processes underlying empathy. Understanding this dependency, however, has been limited by a lack of objective metrics for measuring empathic performance.
Helle Ruff Laursen   +9 more
doaj   +1 more source

Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection [PDF]

open access: yes, 2010
Functional magnetic resonance imaging can demonstrate the functional anatomy of cognitive processes. In patients with refractory temporal lobe epilepsy, evaluation of preoperative verbal and visual memory function is important as anterior temporal lobe ...
Bonelli, S. B.   +7 more
core  

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

More than just statics: Static and temporal dynamic changes in intrinsic brain activity in unilateral temporal lobe epilepsy

open access: yesFrontiers in Human Neuroscience, 2022
BackgroundTemporal lobe epilepsy (TLE) is the most prevalent refractory focal epilepsy and is more likely accompanied by cognitive impairment. The fully understanding of the neuronal activity underlying TLE is of great significance.ObjectiveThis study ...
Chengru Song   +58 more
doaj   +1 more source

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