Results 51 to 60 of about 439,823 (313)

A Hitchhiker's Guide to Functional Magnetic Resonance Imaging [PDF]

Frontiers in Neuroscience, 2016
Functional Magnetic Resonance Imaging (fMRI) studies have become increasingly popular both with clinicians and researchers as they are capable of providing unique insights into brain functions. However, multiple technical considerations (ranging from specifics of paradigm design to imaging artifacts, complex protocol definition, and multitude of ...
Soares, José Miguel Montenegro, Magalhães, Ricardo José Silva, Moreira, Pedro Miguel Silva, Sousa, Alexandre, Ganz, Edward, Sampaio, Adriana, Alves, Victor, Marques, Paulo César Gonçalves, Sousa, Nuno   +8 more
openaire   +4 more sources

Bayesian mapping of brain regions using compound Markov random field priors [PDF]

, 2003
Human brain mapping, i.e. the detection of functional regions and their connections, has experienced enormous progress through the use of functional magnetic resonance imaging (fMRI).
Gössl, Christoff, Fahrmeir, Ludwig, Hennerfeind, Andrea   +2 more
core   +1 more source

Switchable ROS generator and scavenger to prevent the cisplatin induced acute kidney injury and improve efficacy via synergistic chemodynamic/immune therapy

Materials Today Bio
Acute kidney injury (AKI) induced by cisplatin (DDP), which is accompanied with the generation of reactive oxygen species (ROS), is a severe side effect during treatment and restricts the application of DDP.
Yanan Ren, Fei Wu, Linlin Huo, Xiao Wang, Yong Zhang, Mengke Fan, Mingya Tan, Jiayi Zhao, Jingliang Cheng, Zhenghuan Zhao, Jianfeng Bao   +10 more
doaj   +1 more source

More than just statics: Static and temporal dynamic changes in intrinsic brain activity in unilateral temporal lobe epilepsy

Frontiers in Human Neuroscience, 2022
BackgroundTemporal lobe epilepsy (TLE) is the most prevalent refractory focal epilepsy and is more likely accompanied by cognitive impairment. The fully understanding of the neuronal activity underlying TLE is of great significance.ObjectiveThis study ...
Chengru Song, Chengru Song, Chengru Song, Chengru Song, Chengru Song, Chengru Song, Chengru Song, Xiaonan Zhang, Xiaonan Zhang, Xiaonan Zhang, Xiaonan Zhang, Xiaonan Zhang, Xiaonan Zhang, Xiaonan Zhang, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Keran Ma, Keran Ma, Keran Ma, Keran Ma, Keran Ma, Keran Ma, Keran Ma, Kefan Wang, Kefan Wang, Kefan Wang, Kefan Wang, Kefan Wang, Kefan Wang, Kefan Wang, Xinyue Mao, Xinyue Mao, Xinyue Mao, Xinyue Mao, Xinyue Mao, Xinyue Mao, Xinyue Mao, Yajun Lian, Xianchang Zhang, Jinxia Zhu, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng   +58 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Functional Diffusion Magnetic Resonance Imaging

, 2018
Functional diffusion magnetic resonance imaging (fDMRI) is a noninvasive technique that allows elucidating physiological and anatomical changes at a microscopic scale by detection of water molecular displacements in tissue structures. These displacements likely reflect microstructural changes associated with neuronal or glial cells activation.
Rocha Oliveira, Rita Maria, Guadilla, Irene, López-Larrubia, Pilar   +2 more
openaire   +3 more sources

Adaptive Gaussian Markov Random Fields with Applications in Human Brain Mapping [PDF]

, 2005
Functional magnetic resonance imaging (fMRI) has become the standard technology in human brain mapping. Analyses of the massive spatio-temporal fMRI data sets often focus on parametric or nonparametric modeling of the temporal component, while spatial ...
Brezger, Andreas, Fahrmeir, Ludwig, Hennerfeind, Andrea   +2 more
core   +1 more source

Facile synthesis of Gd/Ru-doped fluorescent carbon dots for fluorescent/MR bimodal imaging and tumor therapy

Journal of Nanobiotechnology
Functional metal doping endows fluorescent carbon dots with richer physical and chemical properties, greatly expanding their potential in the biomedical field.
Yupeng Shi, Yaning Xia, Mengyang Zhou, Yifei Wang, Jianfeng Bao, Yong Zhang, Jingliang Cheng   +6 more
doaj   +1 more source

fMRI reveals neural activity overlap between adult and infant pain

eLife, 2015
Limited understanding of infant pain has led to its lack of recognition in clinical practice. While the network of brain regions that encode the affective and sensory aspects of adult pain are well described, the brain structures involved in infant ...
Sezgi Goksan, Caroline Hartley, Faith Emery, Naomi Cockrill, Ravi Poorun, Fiona Moultrie, Richard Rogers, Jon Campbell, Michael Sanders, Eleri Adams, Stuart Clare, Mark Jenkinson, Irene Tracey, Rebeccah Slater   +13 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source