Results 41 to 50 of about 6,916,372 (302)

Weight Status Modulated Brain Regional Homogeneity in Long-Term Male Smokers

Frontiers in Psychiatry, 2022
BackgroundTobacco smoking and being overweight could lead to adverse health effects, which remain an important public health problem worldwide. Research indicates that overlapping pathophysiology may contribute to tobacco addiction and being overweight ...
Mengzhe Zhang, Mengzhe Zhang, Mengzhe Zhang, Mengzhe Zhang, Mengzhe Zhang, Mengzhe Zhang, Mengzhe Zhang, Xinyu Gao, Xinyu Gao, Xinyu Gao, Xinyu Gao, Xinyu Gao, Xinyu Gao, Xinyu Gao, Zhengui Yang, Zhengui Yang, Zhengui Yang, Zhengui Yang, Zhengui Yang, Zhengui Yang, Zhengui Yang, Xiaoyu Niu, Xiaoyu Niu, Xiaoyu Niu, Xiaoyu Niu, Xiaoyu Niu, Xiaoyu Niu, Xiaoyu Niu, Jingli Chen, Jingli Chen, Jingli Chen, Jingli Chen, Jingli Chen, Jingli Chen, Jingli Chen, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Weijian Wang, Weijian Wang, Weijian Wang, Weijian Wang, Weijian Wang, Weijian Wang, Weijian Wang, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang   +69 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Abnormal Granger causal connectivity based on altered gray matter volume and associated neurotransmitters of adolescents with internet gaming disorder revealed by a multimodal neuroimaging study

Developmental Cognitive Neuroscience
Although prior studies have revealed alterations in gray matter volume (GMV) among individuals with internet gaming disorder (IGD). The brain's multifaceted functions hinge crucially on the intricate connections and communication among distinct regions ...
Xiaoyu Niu, Mengzhe Zhang, Xinyu Gao, Jinghan Dang, Jieping Sun, Qiuying Tao, Yan Lang, Weijian Wang, Yarui Wei, Shaoqiang Han, Huayan Xu, Yingkun Guo, Jingliang Cheng, Yong Zhang   +13 more
doaj   +1 more source

More Than Just Statics: Temporal Dynamic Changes in Inter- and Intrahemispheric Functional Connectivity in First-Episode, Drug-Naive Patients With Major Depressive Disorder

Frontiers in Human Neuroscience, 2022
Several functional magnetic resonance imaging (fMRI) studies have demonstrated abnormalities in static intra- and interhemispheric functional connectivity among diverse brain regions in patients with major depressive disorder (MDD).
Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Shuying Li, Jinxia Guo, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng   +71 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

MRI-guided cell membrane-camouflaged bimetallic coordination nanoplatform for combined tumor phototherapy

Materials Today Bio
Nanotechnology for tumor diagnosis and optical therapy has attracted widespread interest due to its low toxicity and convenience but is severely limited due to uncontrollable tumor targeting.
Mengyang Zhou, Yifei Wang, Yaning Xia, Yinhua Li, Jianfeng Bao, Yong Zhang, Jingliang Cheng, Yupeng Shi   +7 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Functional Magnetic Resonance Imaging in Alzheimer' Disease Drug Development. [PDF]

, 2018
While now commonly applied for studying human brain function the value of functional magnetic resonance imaging in drug development has only recently been recognized. Here we describe the different functional magnetic resonance imaging techniques applied
Klöppel, Stefan, Stefan Klöppel, Dukart, Juergen, Ahmed Abdulkadir, Stefan Holiga, Abdulkadir, Ahmed, Holiga, Stefan, Juergen Dukart   +7 more
core   +2 more sources

Tracing of Neuronal Connections in the Human Brain by Magnetic Resonance Imaging in vivo [PDF]

, 1990
Axon degeneration after disruption of fibre tracts in the mammalian nervous system is accompanied by myelin breakdown which leads to changes in its magnetic resonance properties.
Danek, Adrian, Bauer, W. M., Fries, Wolfgang   +2 more
core   +1 more source

Switchable ROS generator and scavenger to prevent the cisplatin induced acute kidney injury and improve efficacy via synergistic chemodynamic/immune therapy

Materials Today Bio
Acute kidney injury (AKI) induced by cisplatin (DDP), which is accompanied with the generation of reactive oxygen species (ROS), is a severe side effect during treatment and restricts the application of DDP.
Yanan Ren, Fei Wu, Linlin Huo, Xiao Wang, Yong Zhang, Mengke Fan, Mingya Tan, Jiayi Zhao, Jingliang Cheng, Zhenghuan Zhao, Jianfeng Bao   +10 more
doaj   +1 more source