Results 41 to 50 of about 734,147 (280)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Abnormal Granger causal connectivity based on altered gray matter volume and associated neurotransmitters of adolescents with internet gaming disorder revealed by a multimodal neuroimaging study

Developmental Cognitive Neuroscience
Although prior studies have revealed alterations in gray matter volume (GMV) among individuals with internet gaming disorder (IGD). The brain's multifaceted functions hinge crucially on the intricate connections and communication among distinct regions ...
Xiaoyu Niu, Mengzhe Zhang, Xinyu Gao, Jinghan Dang, Jieping Sun, Qiuying Tao, Yan Lang, Weijian Wang, Yarui Wei, Shaoqiang Han, Huayan Xu, Yingkun Guo, Jingliang Cheng, Yong Zhang   +13 more
doaj   +1 more source

More Than Just Statics: Temporal Dynamic Changes in Inter- and Intrahemispheric Functional Connectivity in First-Episode, Drug-Naive Patients With Major Depressive Disorder

Frontiers in Human Neuroscience, 2022
Several functional magnetic resonance imaging (fMRI) studies have demonstrated abnormalities in static intra- and interhemispheric functional connectivity among diverse brain regions in patients with major depressive disorder (MDD).
Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yu Jiang, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Yuan Chen, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Ruiping Zheng, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Bingqian Zhou, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ying Wei, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Ankang Gao, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Yarui Wei, Shuying Li, Jinxia Guo, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Shaoqiang Han, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng, Jingliang Cheng   +71 more
doaj   +1 more source

A Pneumatically Actuated Manipulandum for Neuromotor Control Research [PDF]

, 2002
Functional magnetic resonance imaging (fMRI) techniques have great potential for identifying which neural structures are involved in the control of goal-directed reaching movements.
Ropella, Kristina M., Scheidt, Robert A., Suminski, Aaron J   +2 more
core   +1 more source

Implementation and evaluation of simultaneous video-electroencephalography and functional magnetic resonance imaging [PDF]

, 2010
The objective of this study was to demonstrate that the addition of simultaneous and synchronised video to electroencephalography (EEG)-correlated functional magnetic resonance imaging (fMRI) could increase recorded information without data quality ...
Carmichael, D.W., Chaudhary, U.J., Duncan, J.S., Gasston, D., Kokkinos, V., Lemieux, L., Rodionov, R.   +6 more
core   +1 more source

Functional Diffusion Magnetic Resonance Imaging

, 2018
Functional diffusion magnetic resonance imaging (fDMRI) is a noninvasive technique that allows elucidating physiological and anatomical changes at a microscopic scale by detection of water molecular displacements in tissue structures. These displacements likely reflect microstructural changes associated with neuronal or glial cells activation.
Rocha Oliveira, Rita Maria, Guadilla, Irene, López-Larrubia, Pilar   +2 more
openaire   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

MRI-guided cell membrane-camouflaged bimetallic coordination nanoplatform for combined tumor phototherapy

Materials Today Bio
Nanotechnology for tumor diagnosis and optical therapy has attracted widespread interest due to its low toxicity and convenience but is severely limited due to uncontrollable tumor targeting.
Mengyang Zhou, Yifei Wang, Yaning Xia, Yinhua Li, Jianfeng Bao, Yong Zhang, Jingliang Cheng, Yupeng Shi   +7 more
doaj   +1 more source

Cancro da Próstata: O Papel da Ressonância Magnética Multiparamétrica [PDF]

, 2015
Multiparametric Magnetic Resonance Imaging has been increasingly used for detection, localization and staging of prostate cancer over the last years. It combines high-resolution T2 Weighted-Imaging and at least two functional techniques, which include ...
Bilhim, T, Campos Pinheiro, L, Carmo, S, Fialho, J, João, R, Leal, C, Lopes Dias, J, Mateus Marques, R, Pina, J   +8 more
core  

Diagnostic benefits of presurgical fMRI in patients with brain tumours in the primary sensorimotor cortex [PDF]

, 2011
Reliable imaging of eloquent tumour-adjacent brain areas is necessary for planning function-preserving neurosurgery. This study evaluates the potential diagnostic benefits of presurgical functional magnetic resonance imaging (fMRI) in comparison to a ...
Martina Wengenroth, M. Blatow, J. Guenther, M. Akbar, V. M. Tronnier, C. Stippich   +5 more
core   +1 more source