Results 41 to 50 of about 439,823 (313)

More Than Just Statics: Temporal Dynamic Changes in Inter- and Intrahemispheric Functional Connectivity in First-Episode, Drug-Naive Patients With Major Depressive Disorder

open access: yesFrontiers in Human Neuroscience, 2022
Several functional magnetic resonance imaging (fMRI) studies have demonstrated abnormalities in static intra- and interhemispheric functional connectivity among diverse brain regions in patients with major depressive disorder (MDD).
Yu Jiang   +71 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Functional magnetic resonance imaging in schizophrenia

open access: yesDialogues in Clinical Neuroscience, 2010
The integration of functional magnetic resonance imaging (fMRI) with cognitive and affective neuroscience paradigms enables examination of the brain systems underlying the behavioral deficits manifested in schizophrenia; there have been a remarkable increase in the number of studies that apply fMRI in neurobiological studies of this disease.
Raquel E, Gur, Ruben C, Gur
openaire   +3 more sources

The neuronal correlate of bidirectional synesthesia: a combined event-related potential and functional magnetic resonance imaging study

open access: yes, 2007
The neuronal correlate of a rare explicit bi-directional synaesthesia was investigated with numerical and physical size comparison tasks using both functional magnetic resonance imaging and event-related potentials. Interestingly, although participant I.
Cohen Kadosh, K   +8 more
core   +1 more source

MRI-guided cell membrane-camouflaged bimetallic coordination nanoplatform for combined tumor phototherapy

open access: yesMaterials Today Bio
Nanotechnology for tumor diagnosis and optical therapy has attracted widespread interest due to its low toxicity and convenience but is severely limited due to uncontrollable tumor targeting.
Mengyang Zhou   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Functional Magnetic Resonance Imaging

open access: yes, 2006
Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is a powerful approach to defining activity in the healthy and diseased human brain. BOLD fMRI detects local increases in relative blood oxygenation that are most probably a direct consequence of neurotransmitter action and thus reflect local neuronal signalling.
Matthews, P, Jezzard, P
openaire   +3 more sources

Sleep-related consolidation of a visuomotor skill: brain mechanisms as assessed by functional magnetic resonance imaging

open access: yes, 2003
Subjects were trained on a pursuit task in which the target trajectory was predictable only on the horizontal axis. Half of them were sleep deprived on the first post-training night (n = 13).
Frith, Christopher   +11 more
core   +1 more source

Variation in the oxytocin receptor gene is associated with behavioral and neural correlates of empathic accuracy

open access: yesFrontiers in Behavioral Neuroscience, 2014
The neuromodulators oxytocin and serotonin have been implicated in regulating affective processes underlying empathy. Understanding this dependency, however, has been limited by a lack of objective metrics for measuring empathic performance.
Helle Ruff Laursen   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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