Results 21 to 30 of about 175,227 (263)

Genes2FANs: connecting genes through functional association networks [PDF]

BMC Bioinformatics, 2012
Abstract Background Protein-protein, cell signaling, metabolic, and transcriptional interaction networks are useful for identifying connections between lists of experimentally identified genes/proteins. However, besides physical or co-expression interactions there are many ways in which pairs of genes, or their ...
Dannenfelser Ruth, Clark Neil R, Ma'ayan Avi   +2 more
openaire   +3 more sources

Cerebrovascular disease influences functional and structural network connectivity in patients with amnestic mild cognitive impairment and Alzheimer’s disease

Alzheimer’s Research & Therapy, 2018
Background Patients with amnestic mild cognitive impairment (aMCI) and Alzheimer’s disease (AD) show functional and structural connectivity alterations in the default mode network (DMN) while cerebrovascular disease (CeVD) shows functional and structural
Ashwati Vipin, Yng Miin Loke, Siwei Liu, Saima Hilal, Hee Youn Shim, Xin Xu, Boon Yeow Tan, Narayanaswamy Venketasubramanian, Christopher Li-Hsian Chen, Juan Zhou   +9 more
doaj   +1 more source

Decreased Intrinsic Functional Connectivity in First-Episode, Drug-Naive Adolescents With Generalized Anxiety Disorder

Frontiers in Human Neuroscience, 2019
Generalized anxiety disorder (GAD) is characterized by excessive and uncontrollable worry about everyday life. Prior neuroimaging studies have demonstrated that GAD is associated with disruptions in specific brain regions; however, little is known about ...
Fan Yang, Linlin Fan, Tianyi Zhai, Ying Lin, Yuyin Wang, Junji Ma, Mei Liao, Yan Zhang, Lingjiang Li, Linyan Su, Zhengjia Dai   +10 more
doaj   +1 more source

Resting-State Functional Connectivity Difference in Alzheimer’s Disease and Mild Cognitive Impairment Using Threshold-Free Cluster Enhancement

Diagnostics, 2023
The disruption of functional connectivity is one of the early events that occurs in the brains of Alzheimer’s disease (AD) patients. This paper reports a study on the clustering structure of functional connectivity in eight important brain networks in ...
Ramesh Kumar Lama, Goo-Rak Kwon
doaj   +1 more source

Abnormal Intrinsic Functional Interactions Within Pain Network in Cervical Discogenic Pain

Frontiers in Neuroscience, 2021
Cervical discogenic pain (CDP) is mainly induced by cervical disc degeneration. However, how CDP modulates the functional interactions within the pain network remains unclear.
Hong Zhang, Dongqin Xia, Xiaoping Wu, Run Liu, Hongsheng Liu, Xiangchun Yang, Xiaohui Yin, Song Chen, Mingyue Ma   +8 more
doaj   +1 more source

Dynamic Reconfiguration of Visuomotor-Related Functional Connectivity Networks [PDF]

The Journal of Neuroscience, 2016
Cognitive functions arise from the coordination of large-scale brain networks. However, the principles governing interareal functional connectivity dynamics (FCD) remain elusive. Here, we tested the hypothesis that human executive functions arise from the dynamic interplay of multiple networks.
Brovelli, Andrea, Badier, Jean-Michel, Bonini, Francesca, Bartolomei, Fabrice, Coulon, Olivier, Auzias, Guillaume   +5 more
openaire   +3 more sources

Autism-associated Nf1 deficiency disrupts corticocortical and corticostriatal functional connectivity in human and mouse

Neurobiology of Disease, 2019
Children with the autosomal dominant single gene disorder, neurofibromatosis type 1 (NF1), display multiple structural and functional changes in the central nervous system, resulting in neuropsychological cognitive abnormalities.
Ben Shofty, Eyal Bergmann, Gil Zur, Jad Asleh, Noam Bosak, Alexandra Kavushansky, F. Xavier Castellanos, Liat Ben-Sira, Roger J. Packer, Gilbert L. Vezina, Shlomi Constantini, Maria T. Acosta, Itamar Kahn   +12 more
doaj   +1 more source

Decreased Functional Connectivity in the Reward Network and Its Relationship With Negative Emotional Experience After Total Sleep Deprivation

Frontiers in Neurology, 2021
Sleep deprivation (SD) induces a negative emotional experience due to a prolonged time spent awake. However, few studies have focused on the mechanism underlying communication within brain networks or alterations during this emotional deterioration.
Ying Zhang, Ying Zhang, Cimin Dai, Yongcong Shao, Jiaxi Peng, Yan Yang, Yanhong Hou   +6 more
doaj   +1 more source

Reconfiguration of large‐scale functional connectivity in patients with disorders of consciousness

Brain and Behavior, 2020
Introduction Functional connectivity alterations within individual resting state networks (RSNs) are linked to disorders of consciousness (DOC). If these alterations influence the interaction quality with other RNSs, then, brain alterations in patients ...
Darwin E. Martínez, Jorge Rudas, Athena Demertzi, Vanessa Charland‐Verville, Andrea Soddu, Steven Laureys, Francisco Gómez   +6 more
doaj   +1 more source

Network-level functional connectivity alterations in chemotherapy treated breast cancer patients: a longitudinal resting state functional MRI study

Cancer Imaging, 2020
Background Previous studies have found abnormal structural and functional brain alterations in breast cancer survivors undergoing chemotherapy. However, the network-level brain changes following chemotherapy remain unknown.
Yun Feng, Yun Fei Wang, Li Juan Zheng, Zhao Shi, Wei Huang, Long Jiang Zhang   +5 more
doaj   +1 more source