Results 111 to 120 of about 120,490 (305)

Patient-Specific Model-Based Investigation of Speech Intelligibility and Movement during Deep Brain Stimulation

, 2010
Background/Aims: Deep brain stimulation (DBS) is widely used to treat motor symptoms in patients with advanced Parkinson’s disease. The aim of this study was to investigate the anatomical aspects of the electric field in relation to effects on speech and
Hariz, Mawan I., Martinez-Torres, Irene, Hariz, Marwan I,, Zrinzo, Ludvig U.,, Limousin, Patricia,, Martinez-Torres, Irene,, Tripoliti, Elina, Wårdell, Karin,, Limousin, Patricia, Wårdell, Karin, Zrinzo, Ludvig U., Åström, Mattias,, Åström, Mattias, Zrinzo, Ludvic U, Hariz, Mawan I.,, Tripoliti, Elina,   +15 more
core   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

Severe Refractory Obsessive Compulsive Disorder and Depression: Should We Consider Stereotactic Neurosurgery?

Neuropsychiatric Disease and Treatment
Ludvic Zrinzo Unit of Functional Neurosurgery, UCL Queen Square Institute of Neurology, London, UKCorrespondence: Ludvic Zrinzo, Functional Neurosurgery Unit, Department of Clinical & Motor Neurosciences, UCL Institute of Neurology, Second Floor, 33 ...
Zrinzo L
doaj  

Prefrontal–bed nucleus of the stria terminalis physiological and neuropsychological biomarkers predict therapeutic outcomes in depression

Nature Communications
Therapeutic options for refractory depression are urgently needed. We conducted a deep brain stimulation (DBS) randomized controlled trial of the bed nucleus of the stria terminalis (BNST), an extended amygdala structure, and nucleus accumbens (NAc) in ...
Linbin Wang, Yingying Zhang, Yuhan Wang, Qiong Ding, Luling Dai, Kejia Hu, Kuanghao Ye, Xin lv, Xiaoxiao Zhang, Alekhya Mandali, Luis Manssuer, Saurabh Sonkusare, Yijie Zhao, Peng Huang, Xian Qiu, Yixin Pan, Yijie Lai, Dianyou Li, Wei Liu, Shikun Zhan, Bomin Sun, Valerie Voon   +21 more
doaj   +1 more source

Potentially useful outcome measures for clinical research in pediatric neurosurgery [PDF]

, 2005
journal articleThe choice of outcome (or outcomes) and their measurement are critical for a sound clinical trial. Surgeons have traditionally measured simple outcomes such as death, duration of survival, or tumor recurrence but have recently developed ...
Klimo Jr., Paul, Kestle, John R. W.
core  

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Functional neurosurgery, low back pain

, 2020
The presentation covers fuctional neurosurgery and low back pain ...
Pyatikop, Volodymir
core  

Laser speckle imaging identification of increases in cortical microcirculatory blood flow induced by motor activity during awake craniotomy

, 2013
The goal of awake neurosurgery is to maximize resection of brain lesions with minimal injury to functional brain areas. Laser speckle imaging (LSI) is a noninvasive macroscopic technique with high spatial and temporal resolution used to monitor changes ...
Holland, Wim P. J., Dirven, Clemens M. F., Hulscher, Hester, Bakker, Jan, Holland, Wim, Dirven, Clemens, Bakker, Jan; id_orcid, Vincent, Arnaud, Klijn, Eva, Balvers, Rutger, Balvers, Rutger K., Ince, Can, Hulscher, Hester C., Vincent, Arnaud J. P. E.   +13 more
core   +1 more source

Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.
Patricia Zvarova, Christina van der Linden, Ningfei Li, Konstantin Butenko, Thea Berger, Garance M. Meyer, Ilkem Aysu Sahin, Lukas L. Goede, Bahne H. Bahners, Barbara Hollunder, Till A. Dembek, Andrew R. Pines, Martin Reich, Jens Volkmann, Vincent J. J. Odekerken, Rob M. A. de Bie, Xin Xu, Zhipei Ling, Chen Yao, Andrea A. Kühn, Surjo R. Soekadar, Kerstin Ritter, Michael T. Barbe, Veerle Visser‐Vandewalle, Michael D. Fox, Jan Niklas Petry‐Schmelzer, Nanditha Rajamani, Andreas Horn   +27 more
wiley   +1 more source