Results 101 to 110 of about 120,490 (305)

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun   +12 more
wiley   +1 more source

Drop‐Shaped Optical Microfiber Enabled Biomechanical Sensor

open access: yesAdvanced Science, EarlyView.
A novel microforce sensor based on a drop‐shaped optical microfiber is presented herein, designed to characterize the biomechanical properties of single cells and microscale living organisms, achieving a force resolution of 24 nN. Leveraging its high sensitivity, facile miniaturization, excellent flexibility, and robust mechanical stability, this ...
Yan Xu   +7 more
wiley   +1 more source

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

open access: yesAdvanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu   +12 more
wiley   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu   +13 more
wiley   +1 more source

Cognitive outcomes following functional neurosurgery in refractory OCD patients: a systematic review. [PDF]

open access: yesNeurosurg Rev, 2023
Laseca-Zaballa G   +9 more
europepmc   +1 more source

Radiosurgery for Functional Neurosurgery

open access: yesJBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA, 2018
Objective: Radiosurgery has become an important tool in the treatment of various diseases of the nervous system. Besides classical indications such as tumors and arteriovenous malformations, other functional diseases are increasingly becoming as routine procedures in main radiosurgery centers.
openaire   +2 more sources

The Impact of Early Postoperative Blood Pressure Variability and Hypertension Status on 90‐Day Functional Outcomes in Acute Ischemic Stroke due to Large Vessel Occlusion Patients Treated With Mechanical Thrombectomy

open access: yesAGING MEDICINE, EarlyView.
Early postoperative blood pressure variability independently predicts poor 90‐day functional outcomes in AIS‐LVO patients after mechanical thrombectomy, with the adverse effect amplified in those with pre‐existing hypertension. Maintaining stable blood pressure in the early postoperative period may improve recovery in this high‐risk population ABSTRACT
Yunpeng Liu   +4 more
wiley   +1 more source

Case Report: “Stent-within-a-Stent” technique after telescopic flow diverter reconstruction for basilar artery aneurysm with proximal stenosis

open access: yesFrontiers in Surgery
BackgroundComplex basilar artery aneurysms are challenging to treat due to their deep anatomical location and proximity to critical perforating arteries, as well as their frequent fusiform morphology and association with long-segment stenosis or ...
Iroda Mammadinova   +5 more
doaj   +1 more source

The intralaminar thalamus: a review of its role as a target in functional neurosurgery. [PDF]

open access: yesBrain Commun, 2023
Arnts H   +6 more
europepmc   +1 more source

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