Results 131 to 140 of about 5,408,095 (335)

Case Report: “Stent-within-a-Stent” technique after telescopic flow diverter reconstruction for basilar artery aneurysm with proximal stenosis

Frontiers in Surgery
BackgroundComplex basilar artery aneurysms are challenging to treat due to their deep anatomical location and proximity to critical perforating arteries, as well as their frequent fusiform morphology and association with long-segment stenosis or ...
Iroda Mammadinova, Chingiz Nurimanov, Nurtay Nurakay, Karashash Menlibayeva, Serik Akshulakov, Yerbol Makhambetov   +5 more
doaj   +1 more source

Cognitive outcomes following functional neurosurgery in refractory OCD patients: a systematic review. [PDF]

Neurosurg Rev, 2023
Laseca-Zaballa G, Lubrini G, Periañez JA, Simón-Martínez V, Martín Bejarano M, Torres-Díaz C, Martínez Moreno N, Álvarez-Linera J, Martínez Álvarez R, Ríos-Lago M.   +9 more
europepmc   +1 more source

Viral Vector-based Improvement of Optic Nerve Regeneration: Characterization of Individual Axons\u27 Growth Patterns and Synaptogenesis in a Visual Target [PDF]

, 2015
Lack of axon growth ability in the central nervous system poses a major barrier to achieving functional connectivity after injury. Thus, a non-transgenic regenerative approach to reinnervating targets has important implications in clinical and research ...
Blackmore, Murray G., Luo, Xueting, Salgueiro, Yadira, Yungher, Benjamin J.   +3 more
core   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

Advanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv, Yu Cao, Yuhan Wang, Yunhao Wu, Yingying Zhang, Kuanghao Ye, Xian Qiu, Qingfang Sun, Liuguan Bian, Halimureti Paerhati, Valerie Voon, Shikun Zhan, Bomin Sun   +12 more
wiley   +1 more source

Prefrontal–bed nucleus of the stria terminalis physiological and neuropsychological biomarkers predict therapeutic outcomes in depression

Nature Communications
Therapeutic options for refractory depression are urgently needed. We conducted a deep brain stimulation (DBS) randomized controlled trial of the bed nucleus of the stria terminalis (BNST), an extended amygdala structure, and nucleus accumbens (NAc) in ...
Linbin Wang, Yingying Zhang, Yuhan Wang, Qiong Ding, Luling Dai, Kejia Hu, Kuanghao Ye, Xin lv, Xiaoxiao Zhang, Alekhya Mandali, Luis Manssuer, Saurabh Sonkusare, Yijie Zhao, Peng Huang, Xian Qiu, Yixin Pan, Yijie Lai, Dianyou Li, Wei Liu, Shikun Zhan, Bomin Sun, Valerie Voon   +21 more
doaj   +1 more source

Neural spike sorting with spatio-temporal features [PDF]

, 2008
The paper analyses signals that have been measured by brain probes during surgery. First background noise is removed from the signals. The remaining signals are a superposition of spike trains which are subsequently assigned to different families.
Ali Salah, Albert, Archer, Claude, Hochstenbach, Michiel, Hoede, Kees, Meijer, Hil, Meinsma, Gjerrit, Stolk, Chris, Swist, Tomasz, Zyprych, Joanna   +8 more
core   +1 more source

Patient‐Derived 3D‐Bioprinted Intrahepatic Cholangiocarcinoma Models Recapitulate Tumor Autologous Traits and Predict Personalized Adjuvant Therapy

Advanced Science, EarlyView.
Leveraging 3D bioprinting, this study establishes patient‐derived in vitro models of intrahepatic cholangiocarcinoma. These models faithfully recapitulate the histopathology, molecular profiles, and genomic characteristics of the original patient tumors.
Yuce Lu, Liwei Du, Minghao Sun, Kai Zhang, Mingchang Pang, Shangze Jiang, Jiaxun Dong, Xiyue Liu, Bao Jin, Fu Xu, Hang Sun, Jiangang Zhang, Huiyu Yang, Xiaobo Yang, Xin Lu, Yiyao Xu, Haitao Zhao, Shunda Du, Xinting Sang, Yongchang Zheng, Lei Zhang, Xueshuai Wan, Huayu Yang, Yilei Mao   +23 more
wiley   +1 more source

Severe Refractory Obsessive Compulsive Disorder and Depression: Should We Consider Stereotactic Neurosurgery?

Neuropsychiatric Disease and Treatment
Ludvic Zrinzo Unit of Functional Neurosurgery, UCL Queen Square Institute of Neurology, London, UKCorrespondence: Ludvic Zrinzo, Functional Neurosurgery Unit, Department of Clinical & Motor Neurosciences, UCL Institute of Neurology, Second Floor, 33 ...
Zrinzo L
doaj  

Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. [PDF]

, 2018
Adult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas and similar projects have provided a comprehensive understanding of the somatic alterations and ...
GLASS Consortium
core  

Metal‐Supramolecular Drug Delivery System Empowered Meningeal Lymphatic Vessels‐Bridged Intracranial‐Peripheral Dual Immune Modulation for Reversing Glioblastoma Immune Suppression

Advanced Science, EarlyView.
A novel metal‐supramolecular nanoplatform (FLM@VC) enables efficient brain delivery via meningeal lymphatic vessels (MLVs), bypassing the blood‐brain barrier (BBB) through subcutaneous administration. It reprograms tumor‐associated macrophages (TAMs) and remodels the MLVs to promote DC trafficking and CD8+ T cell activation.
Chenxi Zhang, Zhongsheng Xu, Xiaowen Xu, Zening Zhang, Ranran Luo, Pengchen Ren, Yingying Luo, Qiuchi Wu, Xinyu Liu, Guodong Liu, Xiaojing He, Yun Liu   +11 more
wiley   +1 more source