Results 61 to 70 of about 120,490 (305)

Functional neurosurgery

, 2004
É realizada exposição dos objetivos principais da Neurocirurgia Funcional. O campo de ação, limites e filosofia de trabalho desta nova especialidade são revistos à luz da neurofisiologia.The main objetives of the Functional Neurosurgery is presented. The
Marino Junior, Raul
core   +1 more source

Practical Application of Networks in Neurosurgery: Combined 3-Dimensional Printing, Neuronavigation, and Preoperative Surgical Planning

, 2020
BACKGROUND: A plethora of cutting-edge neuroimaging analyses have been developed and published, yet they have not hitherto been realized as improvements in neurosurgical outcomes.
Romero Garcia, Rafael, Yaara, Erez, Owen, Mallory, Poologaindran, Anujan, Hart, Michael G., Oliver, Geoffrey, Merali, Sakinah   +6 more
core   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Brain state-dependent closed-loop modulation of paired associative stimulation controlled by sensorimotor desynchronization

Frontiers in Cellular Neuroscience, 2016
Background: Pairing peripheral electrical stimulation (ES) and transcranial magnetic stimulation (TMS) increases corticospinal excitability when applied with a specific temporal pattern.
Vladislav eRoyter, Alireza eGharabaghi
doaj   +1 more source

Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

Advanced Functional Materials, EarlyView.
A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu, Liangchao Du, Runlin Wen, Kai Zhang, Yu Zhou, Wanrong Ma, Zhiquan Yang, Dingyang Liu, Xing Li   +8 more
wiley   +1 more source

The outcomes of microvascular decompression for primary trigeminal neuralgia: insights from a single-center experience and technical advancements

Frontiers in Surgery
BackgroundMicrovascular decompression (MVD) remains the primary surgical treatment for trigeminal neuralgia due to its positive postoperative results. This study aims to evaluate the outcomes of patients with primary trigeminal neuralgia who underwent ...
Chingiz Nurimanov, Iroda Mammadinova, Karashash Menlibayeva, Assylbek Kaliyev, Yerbol Makhambetov, Serik Akshulakov   +5 more
doaj   +1 more source

Phase-dependent modulation as a novel approach for therapeutic brain stimulation

Frontiers in Computational Neuroscience, 2015
Closed-loop paradigms provide us with the opportunity to optimize stimulation protocols for perturbation of pathological oscillatory activity in brain-related disorders.
Ramin eAzodi-Avval, Alireza eGharabaghi
doaj   +1 more source

Brain tissue oxygen pressure monitoring in awake patients during functional neurosurgery: the assessment of normal values

, 2008
Local brain tissue oxygen (ptiO2) monitoring is frequently applied in patients at risk for cerebral ischemia. To identify ischemic thresholds, the normal range of local brain tissue oxygen pressure (ptiO2) values needs to be established.
Bouma, Gerrit J., Schuurman, P. Richard, Pennings, Frederik A., van den Munckhof, Pepijn   +3 more
core   +1 more source

Current Use of Intraoperative Neurophysiology in Neurosurgery: Supratentorial Part 1.

, 2022
General aim of neurosurgical practice is to both anatomically and physiologically preserve functional neurological structures to ensure higher quality of life.
Seidel, Kathleen, Taskiran, Emine
core   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source