A functional observational battery for evaluation of neurological outcomes in a rat model of acute bacterial meningitis [PDF]
Background Acute bacterial meningitis is a disease with a high mortality and a high incidence of neurological sequelae in survivors. There is an acute need to develop new adjuvant therapies.
Jane Fisher +6 more
doaj +7 more sources
Vision evaluation by functional observational battery, operant behavior test, and light/dark box test in retinal dystrophic RCS rats versus normal rats [PDF]
Background: Vision plays a key role in some behavior tests for rats. Okayama University-type retinal prosthesis (OUReP) is a photoelectric dye-coupled polyethylene film which generates electric potential in response to light and stimulates nearby neurons.
Toshihiko Matsuo +7 more
doaj +2 more sources
Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice. [PDF]
Synthetic stimulants commonly sold as "bath salts" are an emerging abuse problem in the U.S. Users have shown paranoia, delusions, and self-injury. Previously published in vivo research has been limited to only two components of bath salts (mephedrone and methylone).
Marusich JA +3 more
europepmc +4 more sources
Evaluating Changes in Physical Activity and Clinical Outcomes During Post-Hospitalisation Rehabilitation for Persons with COPD: A Prospective Observational Cohort Study [PDF]
Physical activity often remains low after hospitalisation for acute exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD). Although post-hospitalisation rehabilitation has shown to support recovery, its impact on daily activity levels in the ...
Anna L. Stoustrup +6 more
doaj +2 more sources
Objectives: This study was performed to analyse the effects of Sweet Bee Venom(Sweet BV-pure melittin, the major component of honey bee venom) on the central nervous system in rats.
Joong Chul An, Ki Rok Kwon
doaj +2 more sources
Identifying new blood biomarkers of neuroplasticity associated with rehabilitation outcomes after stroke [PDF]
Blood biomarkers in stroke patients seek to guide decision-making in clinical practice, but research on those that respond to brain recovery and their relationship with rehabilitation is still limited.
Nicolás Garcia-Rodriguez +19 more
doaj +2 more sources
Evaluation of Effect Profiles: Functional Observational Battery Outcomes [PDF]
The Functional Observational Battery (FOB) is a neurotoxicity screening assay composed of 25-30 descriptive, scalar, binary, and continuous endpoints. These outcomes have been grouped into six biologically logical domains as a means to interpret the neuroactive properties of tested chemicals (V. C. Moser, 1992, J. Am. Coll. Toxicol.
S J, Baird +3 more
openaire +2 more sources
Alcoholic neuropathy associated with chronic alcohol intake
Alcoholic neuropathy (AN), a debilitating condition that mainly affects chronic alcohol drinkers, is thought to cause lesions in the peripheral nervous system leading to sensory, autonomic, and motor dysfunctions.
Maria Eduarda Tessitore +8 more
doaj +1 more source
Background: In order to be used safely, accurately and reliably, measuring instruments in the health field must first be validated, for which the study of their psychometric properties is necessary. The Short Physical Performance Battery (SPPB) tool is a
Mirian Santamaría-Peláez +7 more
doaj +1 more source
Background Cognitive deficit in Parkinson disease (PD) is an important cause of functional disability in these patients and early detection, with sensitive instruments, can contribute to longitudinal monitoring.
Nariana Mattos Figueiredo Sousa +1 more
doaj +1 more source

