Results 211 to 220 of about 3,398,903 (291)

Radiographic Evaluation of Distal Femoral Sagittal Morphology Following Imageless Robotic-Assisted Total Knee Arthroplasty Using Functional Alignment. [PDF]

J Clin Med
Rossi SMP, Miele G, Carosini A, Capitani P, Benazzo F, Bove F, Andriollo L.   +6 more
europepmc   +1 more source

Orientation Program (Fall - 2019) News - 2019 - Daily Observer

, 2019
Observer, Daily
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Measurement of global longitudinal strain using the apical four-chamber view as a simple indicator for assessing myocardial longitudinal deformation in patients with functional single ventricle. [PDF]

BMC Cardiovasc Disord
Liao M, Pan J, Duan S, Yin H, Ran X, Cui J, Wang L.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Predicting heart failure in asymptomatic diabetes: derivation and internal validation of a clinical prediction model for early detection of diabetic cardiomyopathy. [PDF]

Front Endocrinol (Lausanne)
Cao Y, Chen W, Tian Y, Li Y, Xu L, Tang H.   +5 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Inter-Observer Variability of Gerd-Related Metrics on High-Resolution Manometry and Calculation of the Milan Score. [PDF]

Neurogastroenterol Motil
Sozzi M, Sozzi M, Siboni S, Latorre-Rodriguez AR, Mittal SK, Marabotto E, Pasta A, Calabrese F, Andreatta E, Aldinio G, Coletta M, Penagini R, Lee YY, Ehab SAM, Tee V, Lee RH, Alcala-Gonzalez LG, Rogers B, Hennen MS, Haworth J, Patel A, Patel P, Masuda T, Coss-Adame E, Salvador R, Provenzano L, Nicoletti L, Piccirelli S, Pezzuto E, Tolone S, Asti E, Savarino EV, Gyawali CP.   +32 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Characterization of carotid remodeling in gestational hypertension using radiofrequency data-based vessel stiffness analysis and vector flow imaging. [PDF]

Quant Imaging Med Surg
He Y, Jiang X, Peng Y, Du W, Yuan H, Feng W, Gan L, Zhang J.   +7 more
europepmc   +1 more source