Results 101 to 110 of about 5,164,293 (343)

Information-Based Physics: An Observer-Centric Foundation [PDF]

, 2013
It is generally believed that physical laws, reflecting an inherent order in the universe, are ordained by nature. However, in modern physics the observer plays a central role raising questions about how an observer-centric physics can result in laws ...
Aczél J., Bahreyni N., Baierlein R., Bondi H., Brillouin L., Caticha A., Cox R.T., Cox R.T., Galilei G., Goyal P., Hestenes D., Kevin H. Knuth, Knuth K.H., Knuth K.H., Knuth K.H., Knuth K.H., Kochen S., Pfanzagl J., Schrödinger E., Wheeler J.A.   +19 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Massless Minimally Coupled Fields in De Sitter Space: O(4)-Symmetric States Versus De Sitter Invariant Vacuum [PDF]

, 1993
The issue of de Sitter invariance for a massless minimally coupled scalar field is revisited. Formally, it is possible to construct a de Sitter invariant state for this case provided that the zero mode of the field is quantized properly. Here we take the
A. Folacci, A. Folacci, A. Vilenkin, A. Vilenkin, B. Allen, B. Allen, B. Ratra, B.S. DeWitt, B.S. DeWitt, C. Schomblond, D. Bernard, D. Polarski, E.A. Tagirov, F.G. Friedlander, H. Ford, I. Redmount, J. Collins, J. Garriga, J. Hadamard, Jaume Garriga, Klaus Kirsten, M.R. Brown, N.A. Chernikov, N.D. Birrell, R. Floreanni, R. Rajaraman, S.K. Blau, T.S. Bunch   +27 more
core   +4 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Portrayed emotions in the movie "Forrest Gump" [v1; ref status: indexed, http://f1000r.es/55o]

F1000Research, 2015
Here we present a dataset with a description of portrayed emotions in the movie ”Forrest Gump”. A total of 12 observers independently annotated emotional episodes regarding their temporal location and duration.
Annika Labs, Theresa Reich, Helene Schulenburg, Manuel Boennen, Gehrke Mareike, Madleen Golz, Benita Hartigs, Nico Hoffmann, Sebastian Keil, Malú Perlow, Anne Katrin Peukmann, Lea Noell Rabe, Franca-Rosa von Sobbe, Michael Hanke   +13 more
doaj   +1 more source

Expanding the Area of Gravitational Entropy [PDF]

, 2002
I describe how gravitational entropy is intimately connected with the concept of gravitational heat, expressed as the difference between the total and free energies of a given gravitational system.
Mann, R. B.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Diagnosis of Functional Nodes of Radio Systems with Static Nonlinearities

Известия высших учебных заведений России: Радиоэлектроника, 2016
The problem of diagnosis of functional nodes that are part of radio systems with a static nonlinearity and allowing for the decomposition into components with scalar inputs and outputs.
B. P. Podkopaev, A. S. Iakshin
doaj