Results 131 to 140 of about 3,244,018 (297)

[News Clip: Ground Observers in Practice Alert]

open access: yes, 1956
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about the first practice alert for Fort Worth's Ground Observers ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

First person state/psychological imagery modulates the orbital frontal gyrus and the putamen in individuals with depression

open access: yesFrontiers in Psychiatry
BackgroundPatients with depression appear to imagine scenes preferentially from a 3rd person perspective as if they were observers. Methods: By using functional magnetic resonance imaging we asked patients with major depressive disorder (19, MDD) and ...
Barbara Tomasino   +8 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

The existence and design of functional observers for two-dimensional systems

open access: yes, 2011
This paper is concerned with functional observers for two-dimensional (2D) systems described by the Fornasini–Marchesini local state-space second model. A necessary and sufficient condition is given for the existence of asymptotic functional observers. A
Xu, Huiling   +2 more
core   +1 more source

On Functional Observability of Nonlinear Systems and the Design of Functional Observers with Assignable Error Dynamics

open access: yesIFAC-PapersOnLine
This paper proposes a novel approach for designing functional observers for nonlinear systems, with linear error dynamics and assignable poles. Sufficient conditions for functional observability are first derived, leading to functional relationships between the Lie derivatives of the output to be estimated and the ones of the measured output. These are
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Existence and design of reduced-order scalar functional observers

open access: yes, 2002
In the existing literature, the existence conditions and design procedures for scalar functional observers are available for the cases where the observers’ order p is either p=1 or p=(v-1), where v is the observability index of the matrix pair (C,A ...
J Zhang (7490018)   +2 more
core  

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