Results 171 to 180 of about 1,032,845 (272)

Erratum to: Exploring functional data analysis and wavelet principal component analysis on ecstasy (MDMA) wastewater data

BMC Medical Research Methodology, 2017
Stefania Salvatore, Jørgen G. Bramness, Jo Røislien   +2 more
doaj   +1 more source

Estimating Growth in Height from Limited Longitudinal Growth Data Using Full-Curves Training Dataset: A Comparison of Two Procedures of Curve Optimization-Functional Principal Component Analysis and SITAR. [PDF]

Children (Basel), 2021
Králík M, Klíma O, Čuta M, Malina RM, Kozieł S, Polcerová L, Škultétyová A, Španěl M, Kukla L, Zemčík P.   +9 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Dimensionality reduction of COSMO-RS molecular descriptor using functional principal component analysis (FPCA) for organic solvent mapping. [PDF]

RSC Adv
Ramirez Cardenas LE, Ouaret R, Gerbaud V, Rodriguez Donis I, Thiebaud-Roux S.   +4 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Multilevel Multivariate Functional Principal Component Analysis of Evoked and Induced Event-Related Spectral Perturbations. [PDF]

Stat Biosci
Dong M, Telesca D, Dickinson A, Sugar C, Webb SJ, Jeste S, Levin AR, Shic F, Naples A, Faja S, Dawson G, McPartland JC, Şentürk D.   +12 more
europepmc   +1 more source

Functional nonlinear principal component analysis

Computational Statistics & Data Analysis
Qingzhi Zhong, Xinyuan Song
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

SpaFun: discovering domain-specific spatial expression patterns and new disease-relevant genes using functional principal component analysis. [PDF]

Brief Bioinform
Jiang X, Guo Y, Guo L, Zhong L, Wang J, Xiao G, Li Q, Xu L.   +7 more
europepmc   +1 more source