Results 61 to 70 of about 365,137 (249)
EntropyOver the past decade and a half, dynamic functional imaging has revealed low-dimensional brain connectivity measures, identified potential common human spatial connectivity states, tracked the transition patterns of these states, and demonstrated ...
David Sutherland Blair +2 more
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G3: Genes, Genomes, Genetics, 2016 We previously proposed a simple regression-based method to map quantitative trait loci underlying function-valued phenotypes. In order to better handle the case of noisy phenotype measurements and accommodate the correlation structure among time points ...
Il-Youp Kwak +3 more
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Function-on-function linear quantile regression
Mathematical Modelling and Analysis, 2022 In this study, we propose a function-on-function linear quantile regression model that allows for more than one functional predictor to establish a more flexible and robust approach. The proposed model is first transformed into a finitedimensional space
Ufuk Beyaztas, Han Lin Shang
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Functional quantile principal component analysis
BiostatisticsSummary This paper introduces functional quantile principal component analysis (FQPCA), a dimensionality reduction technique that extends the concept of functional principal components analysis (FPCA) to the examination of participant-specific quantiles curves.
Méndez-Civieta, Álvaro +3 more
openaire +2 more sources
Functional Principal Components Analysis by Choice of Norm
Journal of Multivariate Analysis, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ocaña, F.A. +2 more
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Optimization of fermentation technology of functional lotus leaf tea by response surface-principal component analysis [PDF]
Zhongguo niangzaoUsing lotus leaf as raw material, a functional lotus leaf tea was prepared by fermentation with strong-flavor (Nongxiangxing) Daqu. Using the total flavonoids content, total phenols content and sensory score as evaluation indexes, the effect of Daqu ...
MIAO Yuanxin, BI Jinhua, PENG Xinyu, GAO Jia, WANG Jiaying, OUYANG Qianqian
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source