Results 71 to 80 of about 1,032,845 (272)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
MULTILEVEL SPARSE FUNCTIONAL PRINCIPAL COMPONENT ANALYSIS [PDF]
, 2010 The basic observational unit in this paper is a function. Data are assumed to have a natural hierarchy of basic units. A simple example is when functions are recorded at multiple visits for the same subject. Di et al.
Crainiceanu, Ciprian M., Di, Chong-Zhi
core +1 more source
Assessing extrema of empirical principal component functions
, 2006 The difficulties of estimating and representing the distributions of functional data mean that principal component methods play a substantially greater role in functional data analysis than in more conventional finite-dimensional settings.
Hall, Peter, Vial, Céline
core +2 more sources
MULTILEVEL FUNCTIONAL PRINCIPAL COMPONENT ANALYSIS FOR HIGH-DIMENSIONAL DATA [PDF]
, 2010 We propose fast and scalable statistical methods for the analysis of hundreds or thousands of high dimensional vectors observed at multiple visits. The proposed inferential methods avoid the difficult task of loading the entire data set at once in the ...
Caffo, Brian +5 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
EntropyOver the past decade and a half, dynamic functional imaging has revealed low-dimensional brain connectivity measures, identified potential common human spatial connectivity states, tracked the transition patterns of these states, and demonstrated ...
David Sutherland Blair +2 more
doaj +1 more source
Adaptive Functional Principal Component Analysis
, 2023 We introduce Adaptive Functional Principal Component Analysis, a novel method to capture directions of variation in functional data that exhibit sharp changes in smoothness. We first propose a new adaptive scatterplot smoothing technique that is fast and scalable, and then integrate this technique into a probabilistic FPCA framework to adaptively ...
de la Garza, Angel Garcia +3 more
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Optimization of fermentation technology of functional lotus leaf tea by response surface-principal component analysis [PDF]
Zhongguo niangzaoUsing lotus leaf as raw material, a functional lotus leaf tea was prepared by fermentation with strong-flavor (Nongxiangxing) Daqu. Using the total flavonoids content, total phenols content and sensory score as evaluation indexes, the effect of Daqu ...
MIAO Yuanxin, BI Jinhua, PENG Xinyu, GAO Jia, WANG Jiaying, OUYANG Qianqian
doaj +1 more source
IET Science, Measurement & Technology, 2022 This study is for the case where the available data of power transformer oil–paper insulation is limited to a small amount furfural data, to solve the problems in oil–paper insulation degradation modelling, such as few samples available, unknown function
Yuehan Qu +4 more
doaj +1 more source