Results 111 to 120 of about 1,002,594 (295)

Principal Component Analysis applied to digital image compression [PDF]

open access: yesEinstein (São Paulo), 2012
Objective: To describe the use of a statistical tool (Principal ComponentAnalysis – PCA) for the recognition of patterns and compression,applying these concepts to digital images used in Medicine.Methods: The description of Principal Component Analysis ...
Rafael do Espírito Santo
doaj   +2 more sources

Modelling intra-daily volatility by functional data analysis: an empirical application to the spanish stock market [PDF]

open access: yes
We propose recent functional data analysis techniques to study the intra-daily volatility. In particular, the volatility extraction is based on functional principal components and the volatility prediction on functional AR(1) models.
Esther Ruiz, Juan Romo, Kenedy Alva
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Common functional component modelling [PDF]

open access: yes
Functional data analysis (FDA) has become a popular technique in applied statistics. In particular, this methodology has received considerable attention in recent studies in empirical finance.
Alois Kneip, Michal Benko
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Spatial Risk Premium on Weather Derivatives and Hedging Weather Exposure in Electricity [PDF]

open access: yes
Due to dependency of energy demand on temperature, weather derivatives enable the effective hedging of temperature related fluctuations. However, temperature varies in space and time and therefore the contingent weather derivatives also vary. The spatial
Maria Osipenko, Wolfgang Karl Härdle
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Análisis exploratorio de variables regionalizadas con métodos funcionales Exploratory Analysis of Regionalized Variables with Functional Methods

open access: yesRevista Colombiana de Estadística, 2007
Se muestra cómo las estadísticas descriptivas funcionales y el análisis en componentes principales funcional (ACPF) pueden emplearse en la evaluación empírica del supuesto de estacionariedad considerado en la modelación de variables regionalizadas.
RAMÓN GIRALDO
doaj  

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