Results 101 to 110 of about 147,066 (311)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Functional Programming is Free
CoRR, 2015 A paper has recently been published in SIAM-JC. This paper is faulty: 1) The standard requirements about the definition of an algorithm are not respected, 2) The main point in the complexity study, namely the functional programming component, is absent. The Editorial Board of the SIAM JC had been warned a confirmed publication would be openly commented,
openaire +2 more sources
Declarative programming for artificial intelligence applications
, 2015 In this talk, I will consider some possible extensions to existing functional programming languages that would make them more suitable for the important and growing class of artificial intelligence applications.
Lloyd, John
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
3D Dynamic Programming Approach to Functional Equations with Applications
Journal of Function Spaces, 2020 This article demonstrates the graphical existence of a single fixed point while imposing the contractive condition of Chatterjea type F-contraction on F-metric space (briefly as F-MS). We present two examples that verify the validity of the results given
Awais Asif +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
International Journal of Nephrology, 2012 Several clinical and experimental studies support the hypothesis that foetal programming is an important determinant of nephropathy, hypertension, coronary heart disease, and type 2 diabetes during adulthood.
Maria C. P. Franco +5 more
doaj +1 more source
Common Subexpression Elimination in a Lazy Functional Language [PDF]
, 1997 Common subexpression elimination is a well-known compiler optimisation that saves time by avoiding the repetition of the same computation. To our knowledge it has not yet been applied to lazy functional programming languages, although there are several ...
Chitil, Olaf
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Aspect−Oriented Programming with Type Classes
, 2007 We consider the problem of adding aspects to a strongly typed language which supports type classes. We show that type classes as supported by the Glasgow Haskell Compiler can model an AOP style of programming via a simple syntax-directed transformation ...
Sulzmann, Martin +5 more
core +1 more source