A curated transcriptome dataset collection to investigate the functional programming of human hematopoietic cells in early life. [PDF]
F1000Res, 2016 Rahman M +6 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Multi-functional Reversible Gate for Programmable Silicon Photonics
, 2023 GR.Mahendra Babu, G.Parameshwaran
openalex +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Synthesis of Bidirectional Programs from Examples with Functional Dependencies
Bach Nguyen Trong +2 more
openalex +1 more source
Establishing a Comparative Best Effort Physical Performance and Physio-Behavioral Pain Component Baseline for Use in a Functional Restoration Program [PDF]
Brian Kovacic +2 more
openalex +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
The maternal-infant microbiome axis as an epigenetic and immunometabolic orchestrator: redefining early-life programming and precision interventions for lifelong women's and children's health. [PDF]
Infect ImmunMukherjee A.
europepmc +1 more source
On coinductive equivalences for higher-order probabilistic functional programs
, 2014 Ugo Dal Lago +2 more
openalex +2 more sources
Introducing computer science using a breadth-first approach and functional programming [PDF]
, 2000 Scott Vandenberg, Michael Wollowski
openalex +1 more source