Results 121 to 130 of about 9,875,957 (314)

Representing functional data in reproducing Kernel Hilbert Spaces with applications to clustering and classification [PDF]

open access: yes
Functional data are difficult to manage for many traditional statistical techniques given their very high (or intrinsically infinite) dimensionality. The reason is that functional data are essentially functions and most algorithms are designed to work ...
Alberto Muñoz, Javier González
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Connecticut Council on Developmental Disabilities

open access: yes, 2011
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 26, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/26/11Official website of the Connecticut State Properties Review Board.

core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Other title: Connecticut Council on Developmental Disabilities

open access: yes, 2015
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 26, 2011).; At head of title: State of Connecticut.; Harvested from the web on 11/19/15Official website of the Connecticut State Properties Review Board. Provides

core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Other title: Connecticut Council on Developmental Disabilities

open access: yes, 2014
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 26, 2011).; At head of title: State of Connecticut.; Harvested from the web on 10/17/14Official website of the Connecticut State Properties Review Board. Provides

core  

Enhanced thermo-mechanical properties of carbon fiber reinforced thermoresistant polymer, a blend of di-functional epoxy bisphenol A and a tri-functional epoxy Tactix 742 [PDF]

open access: yes
Fiber reinforced polymer composite structures are particularly vulnerable to high temperatures as their strength drastically reduces under elevated temperature conditions.
Senevirathna, Sandhya Rani   +4 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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