Results 141 to 150 of about 9,875,957 (314)

Other title: Connecticut Council on Developmental Disabilities

open access: yes, 2016
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 26, 2011).; At head of title: State of Connecticut.; Harvested from the web on 11/14/16Official website of the Connecticut State Properties Review Board. Provides

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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Functional properties of dehulled red gram and lentil sourced from organic and non-organic sources: A Comparative evaluation

open access: yes, 2016
The functional properties of the selected legume flours from organic and non-organic sources were studied. The chosen legume samples were decorticated red gram (Cajanus cajan) and lentil (Lens culinaris).
Divya Ramesh, Rajesh, D., Jamuna Prakash
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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Aboveground dominant functional group predicts belowground properties in an alpine grassland community of western China

open access: yes, 2011
It has been suggested that above and belowground interactions produce important feedbacks in natural ecosystems. It is necessary to study the relationships between aboveground plant functional group traits and belowground biomass and soil chemical ...
Wu Gao-Lin, Wu, GL, Li Wei, Shi Zhi-Hua
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Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Anti-inflammatory, antioxidant and hypolipidemic properties of nutraceutical and functional foods

open access: yes, 2015
Anti-inflammatory, antioxidant and hypolipidemic properties of nutraceutical and functional ...
Vincenzo Longo
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Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A property of Green's function

open access: yes, 1995
Let \(k\) be a positive integer, \(M_0\) and \(M_1\) subsets of \(\{0,1,\dots,k-1\}\) such that the sum of their cardinalities is \(k\). Suppose that the solution \(u=u(x)\) of the boundary value problem \(u^{(k)}=f\) in \((0,1)\), \(u^{(i)}=0\) for \(i\in M_0\), \(u^{(j)}(1)=0\) for \(j\in M_1\) with \(f\) not changing sign in \((0,1)\) can be ...
openaire   +2 more sources

Bayesian Functional Data Analysis Using WinBUGS [PDF]

open access: yes
We provide user friendly software for Bayesian analysis of functional data models using \pkg{WinBUGS}~1.4. The excellent properties of Bayesian analysis in this context are due to: (1) dimensionality reduction, which leads to low dimensional projection ...
Ciprian M. Crainiceanu   +1 more
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