Results 151 to 160 of about 15,977,825 (398)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Cellulose nanocrystals: synthesis, functional properties, and applications
Nanotechnology, Science and Applications, 2015 Johnsy George, SN Sabapathi Food Engineering and Packaging Division, Defence Food Research Laboratory, Siddarthanagar, Mysore, Karnataka, India Abstract: Cellulose nanocrystals are unique nanomaterials derived from the most abundant and almost ...
George J, Sabapathi SN
doaj
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Cogent Food & Agriculture, 2017 Starches extracted from banana (Honduras variety) and plantain (Agbagba variety) were modified by pre-gelatinization, oxidation and acetylation. Native and modified starches were evaluated for chemical, functional and pasting properties. Total starch (TS)
Ganiyat O. Olatunde +2 more
doaj +1 more source
Certification of programs with computational effects
, 2014 In purely functional programming languages imperative features, more generally computational effects are prohibited. However, non-functional lan- guages do involve effects.
Ekici, Burak
core
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Differential resistance to distortion as a functional property of two structural parameters of two dimensional line drawings [PDF]
, 1968 R. F. Cowan, W. D. Blissj
openalex +1 more source
On the Functional Properties of AGR
Catalan Working Papers in Linguistics, 1991 This paper is concemed with the properties of the Agreement node: Person and Number. We analyze the role that each of these elements plays in the sentence. It will be claimed that Person is the Nominative Case assigner, whereas Number marks the most prominent argument of the predicate.
openaire +3 more sources
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source