Results 91 to 100 of about 1,610,238 (288)

Adaptation and implementation of a process of innovation and design within a SME [PDF]

, 2014
A design process is a sequence of design phases, starting with the design requirement and leading to a definition of one or several system architectures. For every design phase, various support tools and resolution methods are proposed in the literature.
AMMAR, Adel Amin, NADEAU, Jean-Pierre, SCARAVETTI, Dominique   +2 more
core  

Construction of Liapunov functionals for linear Volterra integrodifferential equations and stability of delay systems

Electronic Journal of Qualitative Theory of Differential Equations, 2000
Inspired by the construction of a new Liapunov functional for linear Volterra integrodifferential equations, we prove some general stability theorems for functional differential equations with infinite delay and weaken the usual requirement for positive ...
Bo Zhang
doaj   +1 more source

Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation. [PDF]

Sci Adv, 2022
Wang F, Tan P, Zhang P, Ren Y, Zhou J, Li Y, Hou S, Li S, Zhang L, Ma Y, Wang C, Tang W, Wang X, Huo Y, Hu Y, Cui T, Niu C, Wang D, Liu B, Lan Y, Yu J.   +20 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Design for Affect: A Core Competency for the 21st Century

GfK Marketing Intelligence Review, 2015
Consumers purchase products with the objective of reducing pain, increasing pleasure or both. Product aesthetics primarily contribute to enhancing consumer pleasure, and utilitarian attributes, such as product functionality, primarily help reduce ...
Chitturi Ravindra
doaj   +1 more source

A functional requirement for sex-determination M/m locus region lncRNA genes in Aedes aegypti female larvae. [PDF]

Sci Rep, 2021
Mysore K, Hapairai LK, Li P, Roethele JB, Sun L, Igiede J, Misenti JK, Duman-Scheel M.   +7 more
europepmc   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Identifying Non-Functional Requirements From Unconstrained Documents Using Natural Language Processing and Machine Learning Approaches

IEEE Access
Requirements engineering is the first phase in software development life cycle and it also plays one of the most important and critical roles. Requirement document mainly contains both functional requirements and non-functional requirements.
Qais A. Shreda, Abualsoud A. Hanani
doaj   +1 more source

Vector fields on mapping spaces and a converse to the AKSZ construction [PDF]

, 2012
The well-known AKSZ construction (for Alexandrov--Kontsevich--Schwarz--Zaboronsky) gives an odd symplectic structure on a space of maps together with a functional $S$ that is automatically a solution for the classical master equation $(S,S)=0$. The input
Voronov, Theodore Th.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source