Results 41 to 50 of about 5,666,463 (234)
Revista Facultad de Ingeniería, 2022 During the last two decades, the application of Goal-Oriented Requirements Engineering has increased in software projects, mainly because this approach is useful during the requirements analysis process and supports the realization of tasks such as ...
Francy-Idaly Muelas-Muelas +2 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Functional Requirements for Authority Data - A Conceptual Model
, 2011 This book represents one portion of the extension and expansion of the Functional Requirements for Bibliographic Records. FRBR has been published as Nr 19 in the present Series.
IFLA Working Group on Functional Requirements and Numbering of Authority Records (FRANAR)
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
ANALYSIS OF A DEVICE FOR WEDM BY MEANS OF PRICIPLES SPECIFIC TO AXIOMATIC DESIGN
Nonconventional Technologies Review, 2016 The research problem was the design of a device for wire electrical discharge machining adapted on a ram electrical discharge machine. A solution able to fulfil the initial requirements was identified.
Gheorghe Bosoanca +3 more
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Functional requirements for bibliographic records: a new practice for the arrangement of bibliographic records [PDF]
تحقیقات اطلاعرسانی و کتابخانههای عمومی, 2008 Functional Requirements for Bibliographic Records (FRBR) is a conceptual model for the arrangement of bibliographic records in catalogs and databases which was proposed in IFLA 1997, following a plan for revising Anglo-American Cataloging Rules (AACR ...
Mohammadamin Erfanmanesh +1 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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REQUIREMENTS AND SOLUTIONS FOR A DEVICE FOR WIRE ELECTRICAL DISCHARGE MACHINING
Nonconventional Technologies Review, 2021 Rectilinear kerfs in workpieces made of hard electroconductive materials can be made by wire erosion electrical discharge machining. However, since machine tools intended for such machining are rarer and more expensive, the problem of using devices for ...
Laurentiu Slatineanu +6 more
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