Results 71 to 80 of about 8,831,063 (384)

Development of safety technology for rise assisting robot “Resyone Plus”

open access: yesNihon Kikai Gakkai ronbunshu, 2018
Human safety is essential for nursing care robots, which have codependent relationships with human. The international safety standard for personal care robots (ISO 13482) is the key to human safety.
Yohei KUME   +2 more
doaj   +1 more source

Functional foods : a conceptual model for assessing their safety and effectiveness [PDF]

open access: yes, 2002
This report shows that the product-diet dilemma can be solved by developing a predictive model. The model integrates food intake data, dynamic consumption patterns and the production chain model and combines them with a risk-benefit ...
Dekker, M., Jongen, W.M.F., Plaami, S.P.
core   +1 more source

Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem Cell Trial of Recovery EnhanceMent After Stroke (STEMS) Pilot Randomized, Controlled Trial (ISRCTN 16784092) [PDF]

open access: yes, 2006
Background and Purpose - Loss of motor function is common after stroke and leads to significant chronic disability. Stem cells are capable of self-renewal and of differentiating into multiple cell types, including neurones, glia, and vascular cells.
Bath, Philip M.W.   +7 more
core   +1 more source

Electromagnetic Risk Analysis for EMI Impact on Functional Safety With Probabilistic Graphical Models and Fuzzy Logic

open access: yesIEEE Letters on Electromagnetic Compatibility Practice and Applications, 2020
For the functional safety of complex systems such as road vehicles, sufficient immunity of the safety-related electronic, electrical and programmable electronic systems to the anticipated electromagnetic environment is required.
L. Devaraj, A. Ruddle, A. Duffy
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Research on the System Architecture of EV Motor Control Unit Based on Functional Safety

open access: yesKongzhi Yu Xinxi Jishu, 2018
This paper presented the basic methods of hazard analysis and risk assessment which based on the functional safety related standards, and then the safety goal and ASIL of EV motor control unit have been derived according to HARA.
WU Lixun   +3 more
doaj  

Case Report: Morphologic and Functional Characteristics of Intestinal Mucosa in a Child With Short Bowel Syndrome After Treatment With Teduglutide: Evidence in Favor of GLP-2 Analog Safety [PDF]

open access: gold, 2022
Enrico Costantino Falco   +9 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Designing a Method for Identifying Functional Safety and Cybersecurity Requirements Utilizing Model-Based Systems Engineering

open access: yesApplied System Innovation
The increasing number and complexity of cyber–physical systems in vehicles necessitate a rigorous approach to identifying functional safety and cybersecurity hazards during the concept phase of product development.
Bastian Nolte   +2 more
doaj   +1 more source

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