Results 81 to 90 of about 8,831,063 (384)

Design of SOC Based SRAM Cluster for Reliability and Functional Safety Applications [PDF]

open access: bronze, 2021
Dr.A. Ranganayakulu   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Functional planning and occupational safety of milk production in cold loose housing barns [PDF]

open access: yes, 2004
The study charted the most serious occupational hazards of cold loose housing barns. Furthermore, the study gave a good general picture of cold loose housing barns (CLHB) in dairy production.
Karttunen, Janne
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Road vehicles functional safety in accordance with series ISO 26262 standards [PDF]

open access: yesTehnika, 2015
Development and application of new electrical/electronic systems carries with it certain risks of software and hardware failures that need to be identified and reduced to minimum level.
Salihović Sabira S.   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Safety assessment of virtualization computing platform for avionics system of civil aircraft

open access: yesXibei Gongye Daxue Xuebao
Aiming at the main problems that affect the security of airborne computing platform after virtualization, such as time-space isolation, fault isolation and schedulability, this paper studies the security level evaluation of airborne computing platform ...
YANG Huan   +4 more
doaj   +1 more source

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