Results 71 to 80 of about 667,116 (261)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Functional Safety Support for the Specialized Computers with Combined Fault-Tolerance Based on the Checkpoints Technique

Безопасность информационных технологий, 2012
The paper considers the issues of functional safety (reliability) support for the specialized computers with combined fault-tolerance. The combined fault-tolerance is analyzed; the criterion is reliable functioning probability.
A. E. Alexandrovich, G. G. Novikov, V. O. Chuckanov, I. M. Yadykin   +3 more
doaj  

Functional Safety-Oriented Risk Analysis of Heavy Vehicle Platooning

Communications
In this paper is presented platooning as a promising approach to reduce the greenhouse gas emissions, fuel consumption, and operation costs in heavy traffic. Attention is given to a risk assessment of vehicle-to-vehicle (V2V) communication in the context
Luboš Mikula, Jan Famfulík
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk Reduction Evaluation of Prescriptive Technical Codes for Hydrogen Refueling Stations Using LOPA

Energies
This study evaluates the risk reduction performance of prescriptive technical codes applied to hydrogen refueling stations using a Layer of Protection Analysis (LOPA) approach.
Yonggyu Kim, Jongbeom Park, Shintak Han, Heewon Song, Heesoo Chung, Keunwon Lee, Gwyam Shin, Seungho Jung   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Time-Sensitive Networking to Improve the Performance of Distributed Functional Safety Systems Implemented over Wi-Fi. [PDF]

Sensors (Basel), 2023
Morato A, Vitturi S, Tramarin F, Zunino C, Cheminod M.   +4 more
europepmc   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

HCCA-SAFE: A Hybrid Cascaded Control Architecture for FPGA-Based Fault Injection in Safety-Critical Automotive SoCs

Micromachines
Automotive System-on-Chips (SoCs) must meet stringent functional safety standards, such as ISO 26262 and IEC 61508, to ensure reliable operation under hardware faults. FPGA-based fault injection has emerged as a practical and cost-effective technique for
Jiajun He, Yuanhao Zhang, Weijie Lu, Yi Liu, Changqing Xu, Xinfang Liao, Yintang Yang   +6 more
doaj   +1 more source

Qualitative and Quantitative Risk Analysis and Safety Assessment of Unmanned Aerial Vehicles Missions Over the Internet

IEEE Access, 2019
In the last few years, unmanned aerial vehicles (UAVs) are making a revolution as an emerging technology with many different applications in the military, civilian, and commercial fields.
Azza Allouch, Anis Koubaa, Mohamed Khalgui, Tarek Abbes   +3 more
doaj   +1 more source