Results 61 to 70 of about 140,548 (311)
Hybrid meta-heuristic frameworks : a functional approach [PDF]
, 2013 Problems requiring combinatorial optimisation are routinely encountered in research and applied computing. Though polynomial-time algorithms are known for certain problems, formany practical problems, frommundane tasks in scheduling through to exotic ...
Senington, Richard James
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
, 2009 Riding's (1991) wholist-analytic dimension of cognitive style proposes a unidimensional view of global-analytic constructs, however, very little empirical evidence exists in support of a relationship between the styles in the wholist-analytic family ...
Davies, Joanne, Davies, Jo
core
08 The Neologism Reception in Modern Times
International Journal of Social and Educational Innovation, 2014 Seen in its historical evolution, lexical innovation throughout the literary text illustrates through numerous acts of language efforts to enrich our modern culture with new lexical expressive elements. The ideas, imagination games has promotes terms and
Cristina Eva SAUCIUC
doaj
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Styl indywidualny w perspektywie genologii lingwistycznej
Stylistyka, 2021 The author of the article analyses the relations between the category of genre and the one of style on three different planes: • lndividual style - functional style (language variety) • lndividual style - genre style (pattern) • Individual style ...
BOŻENA WITOSZ
doaj
Mediterranean Journal of Clinical Psychology, 2014 Background: Despite the role of metacognition in psychopathology, no studies have explored this construct in the area of gastrointestinal disorders.
Maria Catena Quattropani +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Funkcionalʹnaâ stilistika i diskursologiâ v sovremennoj lingvističeskoj paradigme
Stylistyka, 2019 Relations between functional style and discourse, discourse typology and style, functional style boundaries are viewed in the article. It is shown that functional stylistics and discourse studies are interconnected in the modem linguistic paradigm.
Tatʹâna А. Voroncova
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source