Results 71 to 80 of about 871,560 (293)

Dysfunctional metacognitive beliefs and gastrointestinal disorders. Beyond an ‘organic’/‘functional’ categorization in the clinical practice

open access: yesMediterranean Journal of Clinical Psychology, 2014
Background: Despite the role of metacognition in psychopathology, no studies have explored this construct in the area of gastrointestinal disorders.
Maria Catena Quattropani   +3 more
doaj   +1 more source

De Branges spaces and Krein's theory of entire operators

open access: yes, 2015
This work presents a contemporary treatment of Krein's entire operators with deficiency indices $(1,1)$ and de Branges' Hilbert spaces of entire functions.
A. Baranov   +30 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Funkcionalʹnaâ stilistika i diskursologiâ v sovremennoj lingvističeskoj paradigme

open access: yesStylistyka, 2019
Relations between functional style and discourse, discourse typology and style, functional style boundaries are viewed in the article. It is shown that functional stylistics and discourse studies are interconnected in the modem linguistic paradigm.
Tatʹâna А. Voroncova
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Nărodnĭ styly a uplatněnĭ nespisovnosti v literatuře

open access: yesStylistyka, 2020
The concept of national styles has not broken through significantly in Czech stylistics, would it concem complex concept (determination by national language and national character - Kareł Svoboda) or limitations to the specificity of national language ...
Peter Mareš
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

FUNCTIONAL LANGUAGE STYLES:

open access: yesAnalele Universităţii "Dunărea de Jos" din Galaţi Fascicula XXIV Lexic comun / lexic specializat
In order to evaluate the use of neologisms, especially anglicisms from the contemporary Romanian language, our purpose is to imagine types of discourses or texts with the above-mentioned loans. We propose an analysis grid, designed with the caption ‘pragmatic-discursive space’ (PDS) to take into account ‘objective’ and ‘subjective’ guidelines in the ...
openaire   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Debata b le Issues in the Historiography of Colloquial Style

open access: yesStylistyka, 2020
This article is devoted to the main issues of elucidating the specifics colloąuial style in the modem theory of the literary language, presented in Slavic linguistics.

doaj  

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