Results 91 to 100 of about 399,556 (306)

Farming styles and cooperatives disputes of swine farmers under economic pressure in southern France [PDF]

, 2010
In Southern France, the regression of swine farms and swine is ongoing. It involves reorientation of socio-professional networks, especially the farmers’ cooperatives.
Commandeur, M.A.M.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Quality-aware model-driven service engineering [PDF]

, 2008
Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Barrett, Ronan, Boskovic, Marko, Hasselbring, Wilhelm, Pahl, Claus   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

О сопоставителънои стилистике русского и 6олгарского языков

Stylistyka, 2021
The paper discusses comparative stylistics which consists of two parts. Part one deals with comparative stylistics of the resources of the Russian and Bulgarian language. Part two analyses the functional styles of the Russian and the Bulgarian language.
ВАЛЕНТИНА АВРАМОВА
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The role of attitudes towards contradiction in psychological resilience: the cortical mechanism of conflicting resolution networks

Scientific Reports
Managing contradictions and building resilience help us overcome life's challenges. Here, we explored the link between attitudes towards contradictions and psychological resilience, examining the role of cortical conflict resolution networks. We enlisted
Zai-Fu Yao, Meng-Heng Yang, Cheng-Ta Yang, Yun-Hsuan Chang, Shulan Hsieh   +4 more
doaj   +1 more source

A New Approach for Quality Management in Pervasive Computing Environments

, 2013
This paper provides an extension of MDA called Context-aware Quality Model Driven Architecture (CQ-MDA) which can be used for quality control in pervasive computing environments.
Adel, Alti, Phillipe, Roose
core   +2 more sources

Challenging the Computational Metaphor: Implications for How We Think [PDF]

, 1999
This paper explores the role of the traditional computational metaphor in our thinking as computer scientists, its influence on epistemological styles, and its implications for our understanding of cognition.
Stein, Lynn Andrea
core