Results 111 to 120 of about 3,456,014 (308)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Application of learning styles for effective mobile learning [PDF]
, 2006 Mobile technologies are increasingly used for learning, both individually and collaboratively, and supported by wireless connectivity, mobile devices have succeeded in achieving anywhere, anytime learning.
Yau, Jane Yin-Kim, Joy, Mike
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Uncovering the functional aspect of translator style: corpus stylistic insights
Humanities & Social Sciences CommunicationsThis study employs a corpus stylistic approach to examine the functional aspect of translator style. It introduces and explores the concept of “translator’s functional style” through a case study of the Chinese-English translation of Lao She’s Er Ma.
Kan Wu
doaj +1 more source
Masticatory Function and Life Style in Aged.
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 1998 Elderly people gain enjoyment in their remaining years from eating, speaking and tasting things, and they find that the oral function is necessary to arouse in them a desire to work for society, in addition to looking after their own health, they find that over function is important.
openaire +3 more sources
Leaf & Stone Corpus (Singapore 2016) Audio
, 2020 Participants reading aloud from the experimental storybooks 'A Fine Day for a New Hat (Singapore English Version)' by Suzy J Styles, Jelena Sucevic & Vanja Kovic, adapted to Singaporean English by Juanita Travels ...
Travers Kumar, Juanita +2 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Construction Stability Analysis of Curved Continuous Rigid Frame Bridges with High Piers
MATEC Web of Conferences, 2018 Taking the curved continuous rigid frame bridges (CRFBs) with high piers as research object, the construction stability of four different styles of main piers were analyzed by finite element (FE) method in three construction stages including the segment ...
Song Guohua, Li Minghui, Che Delu
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Analele Universităţii "Dunărea de Jos" din Galaţi Fascicula XXIV Lexic comun / lexic specializatIn order to evaluate the use of neologisms, especially anglicisms from the contemporary Romanian language, our purpose is to imagine types of discourses or texts with the above-mentioned loans. We propose an analysis grid, designed with the caption ‘pragmatic-discursive space’ (PDS) to take into account ‘objective’ and ‘subjective’ guidelines in the ...
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