Results 131 to 140 of about 39,133 (309)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
COMPREHENSION AND STYLISTIC CHARACTERISTICS OF CALQUES
Fluminensia: Journal for Philological Research, 2003 This paper discusses the factors which affect the semantic understanding of calques. High understanding and widespread acceptance of calques contribute to the stylistic stratification of these expressions.
Marija Turk
doaj
Formalizing On Chip Communications in a Functional Style.
, 2006 This paper presents a formal model for representing {it any} on-chip communication architecture. This model is described mathematically by a function, named $mathit{GeNoC}$. The correctness of $mathit{GeNoC}$ is expressed as a theorem, which states that messages emitted on the architecture reach their expected destination without modification of their ...
Schmaltz, Julien, Borrione, Dominique
openaire +3 more sources
Phraseological Units in Different Functional Styles
, 2006 Funkcionalni stilovi pokazuju razlike u pojavnosti i uporabi niza jezičnih obilježja. U ovome radu autori analiziraju različite uporabe frazeoloških jedinica u različitim jezičnim stilovima, od onih u kojima su frazeološke jedinice rijetke ili ih uopće ...
Kovačević, Barbara +3 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
, 2009 [[abstract]]Research background and purposes Bayesian network has been widely applied in educational field. According to the research of D.C. Wang (2006), tests based on Bayesian network can be on of the best instrument in diagnosis.
Chiang Shun Hsing
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
, 2015 The study aimed to revealing the effects of leadership styles on functional performance on Djedii mills firm in Touggourt ; in addition to investigating the significant statistical differences employee’s perspective to administrative leadership styles ...
باديس, بوخلوة +1 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source