Results 141 to 150 of about 39,133 (309)
The possible initial period origins of the Chavin Jaguar motif
, 2010 For years, the focus of study in the Chavin culture has been on their influence on later cultures. This study is meant to look into the influences that cultures in the Initial Period may have had on the Chavin, in particular, to their famous jaguar ...
Everson, Nathan
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Concepts of Czech Functional Stylistics
, 1992 Foundations of the Czech functional stylistics, including its basic concepts, have been worked out by Bohuslav Havránek in his papers Úkoly spisovného jazyka a jeho kultura (The Tasks of the Standard Language and its Cultivation, cf. esp.
Čechová, Marie
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Studies in Functional Stylistics
The 15 contributions in the present collection can be divided roughly into three groups: (1) Papers directly following up functional stylistics and the theory of language culture, elaborated in the classical period of the Prague Linguistic School.
Nekvapil, Jirí., Chloupek, Jan.
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Family coalitions and restrictive eating disorders in adolescence: a lausanne trilogue play study. [PDF]
Front PsycholCriscuolo M +9 more
europepmc +1 more source
, 2018 Ky punim bëhet në kuadër të fushes së Stilistikës dhe përqendrohet në krahasimin e stileve funksionale në gjuhën angleze dhe shqipe. Pra, objekti i punimit janë stilet funksionale në gjuhën angleze dhe shqipe.
Rragami, Anejda
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source