Results 101 to 110 of about 1,133,350 (295)

Construction of functional surfaces for dental implants to enhance osseointegration. [PDF]

Front Bioeng Biotechnol, 2023
Wang Z, Wang J, Wu R, Wei J.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

CELL CYCLE REGULATION AND INDUCED NEUROGENESIS IN NEURAL STEM CELLS BY TOPOGRAPHICAL STIMULI

IBRO Neuroscience Reports, 2023
Miguel Esteban-Lucía, Jaime Hernández, Silvia García-López, Marta P. Pereira, Isabel Rodríguez   +4 more
doaj   +1 more source

Transformations of harmonic bundles and Willmore surfaces [PDF]

, 2016
Willmore surfaces are the extremals of the Willmore functional (possibly under a constraint on the conformal structure). With the characterization of Willmore surfaces by the (possibly perturbed) harmonicity of the mean curvature sphere congruence ...
Quintino, A. C.
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Editorial: Functional surfaces and biomaterials. [PDF]

Front Bioeng Biotechnol, 2023
Liu Y, Krastev R, Wei J, Jiang M.
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Functional surfaces, films, and coatings with lignin - a critical review. [PDF]

RSC Adv, 2023
Ruwoldt J, Blindheim FH, Chinga-Carrasco G.   +2 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Functional Surfaces via Laser Processing in Nickel Acetate Solution. [PDF]

Materials (Basel), 2023
Stanciu EM, Pascu A, Croitoru C, Roată IC, Cristea D, Tierean MH, Hulka I, Petre IM, Petre IM, Mirza Rosca JC.   +9 more
europepmc   +1 more source