Results 71 to 80 of about 1,135,783 (296)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Interdisciplinary Materials, 2022 A smart liquid gating membrane is a responsive structural material as a pressure‐driven system that consists of solid membrane and dynamic liquid, responding to the external field.
Mengchuang Zhang +9 more
doaj +1 more source
Dynamics and fragmentation mechanism of (CH3-C5H4)Pt(CH3)3 on SiO2 Surfaces
, 2018 The interaction of (CH3-C5H4)Pt(CH3)3 ((methylcyclopentadienyl)trimethylplatinum)) molecules on fully and partially hydroxylated SiO2 surfaces, as well as the dynamics of this interaction were investigated using density functional theory (DFT) and finite
Jeschke, Harald O +2 more
core +1 more source
Bioactive surface functionalization [PDF]
Journal of Applied Polymer Science, 2014 Reactive chemical vapor deposition (CVD) polymerization provides a substrate-independent platform for effective functionalization of virtually any solid substrates, flat, or curved, even with complex geometries. This article reviews bioactive surface functionalization strategies based on CVD polymerization and highlights commonly used surface ...
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Influence of overlay layers on the abrasive wear
Research in Agricultural Engineering, 2006 A problem of machine parts wear decrease and in this way of the economical effectiveness of rapid wearable parts interferes with majority of manufacturing processes.
P. Hrabě, R. Chotěborský, R. Medlín
doaj +1 more source
, 1996 The generalized stacking fault (GSF) energy surfaces have received considerable attention due to their close relation to the mechanical properties of solids.
Alexander H. +8 more
core +1 more source
Functionality‐fragility surfaces
Earthquake Engineering & Structural Dynamics, 2017 SummaryThe evaluation of functionality and its evolution in the aftermath of extreme events and during the restoration phase is a critical step in disaster resilience assessment. To this respect, this paper presents the ‘Functionality‐Fragility Surface’ (FFS), which is a tool for probabilistic functionality and resilience evaluation of damaged ...
Aman Karamlou, Paolo Bocchini
openaire +2 more sources