Results 71 to 80 of about 1,133,350 (295)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Bioactive surface functionalization [PDF]

open access: yesJournal of Applied Polymer Science, 2014
Reactive chemical vapor deposition (CVD) polymerization provides a substrate-independent platform for effective functionalization of virtually any solid substrates, flat, or curved, even with complex geometries. This article reviews bioactive surface functionalization strategies based on CVD polymerization and highlights commonly used surface ...
openaire   +1 more source

Generalized Stacking Fault Energy Surfaces and Dislocation Properties of Silicon: A First-Principles Theoretical Study

open access: yes, 1996
The generalized stacking fault (GSF) energy surfaces have received considerable attention due to their close relation to the mechanical properties of solids.
Alexander H.   +8 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Influence of overlay layers on the abrasive wear

open access: yesResearch in Agricultural Engineering, 2006
A problem of machine parts wear decrease and in this way of the economical effectiveness of rapid wearable parts interferes with majority of manufacturing processes.
P. Hrabě, R. Chotěborský, R. Medlín
doaj   +1 more source

Dynamics and fragmentation mechanism of (CH3-C5H4)Pt(CH3)3 on SiO2 Surfaces

open access: yes, 2018
The interaction of (CH3-C5H4)Pt(CH3)3 ((methylcyclopentadienyl)trimethylplatinum)) molecules on fully and partially hydroxylated SiO2 surfaces, as well as the dynamics of this interaction were investigated using density functional theory (DFT) and finite
Jeschke, Harald O   +2 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Performance prediction of magnetorheological fluid‐based liquid gating membrane by kriging machine learning method

open access: yesInterdisciplinary Materials, 2022
A smart liquid gating membrane is a responsive structural material as a pressure‐driven system that consists of solid membrane and dynamic liquid, responding to the external field.
Mengchuang Zhang   +9 more
doaj   +1 more source

Functionality‐fragility surfaces

open access: yesEarthquake Engineering & Structural Dynamics, 2017
SummaryThe evaluation of functionality and its evolution in the aftermath of extreme events and during the restoration phase is a critical step in disaster resilience assessment. To this respect, this paper presents the ‘Functionality‐Fragility Surface’ (FFS), which is a tool for probabilistic functionality and resilience evaluation of damaged ...
Aman Karamlou, Paolo Bocchini
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy