Results 71 to 80 of about 3,791,469 (306)

On Plant Modularity Traits: Functions and Challenges [PDF]

open access: yesTrends in Plant Science, 2017
On-spot persistence, space occupancy, and recovery after damage are key plant functions largely understudied. Traits relevant to these functions are difficult to assess because of their relationships to plant modularity. We suggest that developing collection protocols for these traits is feasible and could facilitate their inclusion in global syntheses.
Ottaviani, Gianluigi   +4 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Searching for Function: Reconstructing Adaptive Niche Changes Using Geochemical and Morphological Data in Planktonic Foraminifera

open access: yesFrontiers in Ecology and Evolution, 2021
Dead species remain dead. The diversity record of life is littered with examples of declines and radiations, yet no species has ever re-evolved following its true extinction.
Lorna E. Kearns   +4 more
doaj   +1 more source

Functional traits of fossil plants

open access: yesNew Phytologist
SummaryA minuscule fraction of the Earth's paleobiological diversity is preserved in the geological record as fossils. What plant remnants have withstood taphonomic filtering, fragmentation, and alteration in their journey to become part of the fossil record provide unique information on how plants functioned in paleo‐ecosystems through their traits ...
McElwain, Jennifer C.   +14 more
openaire   +5 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Small mammal responses to fire severity mediated by vegetation characteristics and species traits

open access: yesEcology and Evolution, 2022
The frequency of large, high‐severity “mega‐fires” has increased in recent decades, with numerous consequences for forest ecosystems. In particular, small mammal communities are vulnerable to post‐fire shifts in resource availability and play critical ...
Kathryn Culhane   +5 more
doaj   +1 more source

Testing for familial aggregation of functional traits [PDF]

open access: yesStatistics in Medicine, 2009
AbstractIn a genetic epidemiology study of a trait, prior to collecting genotype data the foremost task is to test for familial aggregation and examine heritability. Recently, functional traits have drawn attentions from investigators. Here, to test for familial aggregation of a functional trait in the family studies, a test constructed based on the ...
Yixin, Fang, Yuanjia, Wang
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparison of the Pollen Deposition and Carrying Efficiency of Four Wild Pollinators for Oil-Seed Camellia Trees

open access: yesInsects
To investigate how insect hair morphology influences pollination effectiveness, this study examined four common wild pollinators in Camellia oleifera plantations: two bee species (Colletes gigas and Apis cerana) and two hornet species (Vespa velutina and
Zijian Li   +6 more
doaj   +1 more source

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