Results 31 to 40 of about 290,372 (218)

On Plant Modularity Traits: Functions and Challenges [PDF]

Trends in Plant Science, 2017
On-spot persistence, space occupancy, and recovery after damage are key plant functions largely understudied. Traits relevant to these functions are difficult to assess because of their relationships to plant modularity. We suggest that developing collection protocols for these traits is feasible and could facilitate their inclusion in global syntheses.
Ottaviani, Gianluigi, Martínková, Jana, Herben, Tomáš, Klimešová, Jitka, Pausas, J. G.   +4 more
openaire   +3 more sources

Global relationships in tree functional traits

Nature Communications, 2022
AbstractDue to massive energetic investments in woody support structures, trees are subject to unique physiological, mechanical, and ecological pressures not experienced by herbaceous plants. Despite a wealth of studies exploring trait relationships across the entire plant kingdom, the dominant traits underpinning these unique aspects of tree form and ...
Daniel S. Maynard, Lalasia Bialic-Murphy, Constantin M. Zohner, Colin Averill, Johan van den Hoogen, Haozhi Ma, Lidong Mo, Gabriel Reuben Smith, Alicia T. R. Acosta, Isabelle Aubin, Erika Berenguer, Coline C. F. Boonman, Jane A. Catford, Bruno E. L. Cerabolini, Arildo S. Dias, Andrés González-Melo, Peter Hietz, Christopher H. Lusk, Akira S. Mori, Ülo Niinemets, Valério D. Pillar, Bruno X. Pinho, Julieta A. Rosell, Frank M. Schurr, Serge N. Sheremetev, Ana Carolina da Silva, Ênio Sosinski, Peter M. van Bodegom, Evan Weiher, Gerhard Bönisch, Jens Kattge, Thomas W. Crowther   +31 more
openaire   +10 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Functional traits of fossil plants

New Phytologist
SummaryA minuscule fraction of the Earth's paleobiological diversity is preserved in the geological record as fossils. What plant remnants have withstood taphonomic filtering, fragmentation, and alteration in their journey to become part of the fossil record provide unique information on how plants functioned in paleo‐ecosystems through their traits ...
McElwain, Jennifer C., Matthaeus, William J., Barbosa, Catarina, Chondrogiannis, Christos, O' Dea, Katie, Jackson, Bea, Knetge, Antonietta B., Kwasniewska, Kamila, Nair, Richard, White, Joseph D., Wilson, Jonathan P., Montañez, Isabel P., Buckley, Yvonne M., Belcher, Claire M., Nogué, Sandra   +14 more
openaire   +5 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Animal functional traits: Towards a trait‐based ecology for whole ecosystems

Functional Ecology, 2023
Abstract Functional traits and associated trait‐based concepts have driven rapid innovation in ecology over recent years, with most progress based on insights from plants. However, plants are almost entirely restricted to a single trophic level, and an over‐reliance on plant traits therefore neglects the complexity and importance of biotic ...
Matthias Schleuning, Daniel García, Joseph A. Tobias   +2 more
openaire   +3 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source