Results 51 to 60 of about 305,306 (267)

Animal functional traits: Towards a trait‐based ecology for whole ecosystems

Functional Ecology, 2023
Abstract Functional traits and associated trait‐based concepts have driven rapid innovation in ecology over recent years, with most progress based on insights from plants. However, plants are almost entirely restricted to a single trophic level, and an over‐reliance on plant traits therefore neglects the complexity and importance of biotic ...
Matthias Schleuning, Daniel García, Joseph A. Tobias   +2 more
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Functional diversity and functional traits of periphytic algae during a short-term successional process in a Neotropical floodplain lake

Brazilian Journal of Biology
Due to the lack of knowledge in periphytic algae functional diversity patterns during successional processes in floodplains, the present study aimed to analyze the dynamics of the functional traits and functional diversity of periphytic species during a ...
B Dunck, L Rodrigues, DC Bicudo
doaj   +1 more source

Single Grazing Is More Detrimental to Grasslands Than Mixed Grazing: Evidence From the Response of Functional Traits of Dominant Plants to Grazing Systems

Frontiers in Ecology and Evolution, 2021
Plant functional traits reflect species ecological strategies and determine how plants respond to environmental changes, however, how dominant species in the Inner Mongolia grassland adapt to different grazing systems by changing their functional traits ...
Zheng Wang, Jinghui Zhang, Jinghui Zhang, Zhiyong Li, Huamin Liu, Lixin Wang, Lixin Wang, Wen Wang, Yang Wang, Cunzhu Liang   +9 more
doaj   +1 more source

Testing for familial aggregation of functional traits [PDF]

Statistics in Medicine, 2009
AbstractIn a genetic epidemiology study of a trait, prior to collecting genotype data the foremost task is to test for familial aggregation and examine heritability. Recently, functional traits have drawn attentions from investigators. Here, to test for familial aggregation of a functional trait in the family studies, a test constructed based on the ...
Yixin, Fang, Yuanjia, Wang
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Functional traits mediate the elevational patterns of functional diversity and community structure of mosses in a tropical mountain area

Global Ecology and Conservation
Functional diversity refers to the value, range, and distribution of functional traits within a community, such as the morphological, physiological and behavioral characteristics of species that determine the role a species plays in an ecosystem ...
Liqin Fu, Chengxiu Zhan, Haozhe Wang, Shikai Song, Peng Xu, Lina Zhang, Jiancheng Zhao, De Gao   +7 more
doaj   +1 more source