Results 51 to 60 of about 3,186,814 (251)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Beyond urodynamics: non-invasive approaches to diagnosing detrusor underactivity in men with lower urinary tract symptoms – a systematic review

BMC Urology
Background To evaluate and synthesize existing evidence on non-invasive methods for diagnosing detrusor underactivity (DU) in men presenting with lower urinary tract symptoms (LUTS), focusing on their feasibility and diagnostic accuracy.
Karolina Garbas, Łukasz Zapała, Aleksander Ślusarczyk, Hanna Piekarczyk, Tomasz Piecha, Piotr Radziszewski   +5 more
doaj   +1 more source

Authorship Gender Composition in Urology Literature From 2015 Through 2020

, 2022
To describe the current landscape of first and last female authorship in urology journals relative to the journals’ impact factor. We hypothesized that women would have a smaller proportion of publications in journals with higher impact factors. Eighteen
Kalavar, Meghana, Shah, Aayush, Nassau, Daniel E, Suarez Arbelaez, Maria Camila, Kuchakulla, Manish, Ramasamy, Ranjith, Watane, Arjun, Ory, Jesse   +7 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Sacral neuromodulation success in a long-term multiple sclerosis patient with neurogenic bladder disorder and detrusor underactivity: a case report

African Journal of Urology
Background Multiple sclerosis (MS) is a leading cause of non-traumatic disability in young adults and is frequently associated with lower urinary tract symptoms (LUTS).
Karolina Garbas, Aleksandra Żuk-Łapan, Mateusz Mucha, Tomasz Piecha, Łukasz Zapała, Piotr Radziszewski   +5 more
doaj   +1 more source

Practical tips in urology

, 2016
Practical Tips in Urology is a compact, illustrated reference which provides the reader with practical tips and advice in managing day-to-day urological issues encountered in a clinical setting.
Turna B., Rassweiler J.J., Rané A., Autorino R.   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Recent Advances in treatment of urethral stricture disease in men [version 1; peer review: 2 approved]

F1000Research, 2020
Urethral stricturing is a narrowing of the urethral lumen as a result of ischaemic spongiofibrosis. The main challenge of currently available treatment options is recurrence of the stricture.
Naside Mangir, Christopher Chapple
doaj   +1 more source

Development and validation of a short version of the Female Sexual Function Index in the Spanish population

BMC Women's Health, 2021
Background The Female Sexual Function Index (FSFI) is a commonly used scale for the assessment of female sexual function. Our aim was to develop and validate a Spanish short version of the FSFI.
Laura Mateu Arrom, Montserrat Girabent-Farrés, Mónica González, Joan Palou, Carlos Errando-Smet, Inés Ramírez-García   +5 more
doaj   +1 more source

How did The COVID-19 Pandemic Affect Urology Publications?

, 2022
Objective: To evaluate the effect of the pandemic on the publications related to urology. Methods: All publications about urology in the PubMed database between 2016 and 2020 were reviewed.
Ahmet ASFUROĞLU, Ali YILDIZ, Ateş KADIOĞLU, Murat DİNÇER, Murat Bozlu, Emrah YÜRÜK, Tümay İPEKÇİ   +6 more
core   +1 more source