Results 61 to 70 of about 3,186,814 (251)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The Role of Urodynamics in the Evaluation of Urinary Incontinence: The European Association of Urology Recommendations in 2016

, 2017
This article summarises the European Association Urology guidelines position on the role of urodynamic studies in investigating the problem of urinary incontinence. The guidelines recommend that urodynamics should not be necessary to help decide the best
Nambiar, Arjun K, European Association, of Urology, Chapple, Christopher R, Lemack, Gary E, Burkhard, Fiona Christine   +4 more
core   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

European Association of Urology Guidelines on Vasectomy

, 2012
Context: The European Association of Urology presents its guidelines for vasectomy. Vasectomy is highly effective, but problems can arise that are related to insufficient preoperative patient information, the surgical procedure, and postoperative follow ...
Dohle, Gert R., Diemer, T, Kopa, Z, Krausz, Csilla, Kopa, Zsolt, Thorsten Diemer, Aleksander Giwercman, Jungwirth, Andreas, Krausz, C, Giwercman, Aleksander,, Csilla Krausz, Giwercman, Aleksander, Gert R. Dohle, Jungwirth, A, Andreas Jungwirth, Dohle, Gert, Giwercman, A, Diemer, Thorsten, Zsolt Kopa, Lund University.   +19 more
core   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Hybrid Continuum Robot Designs and Architectures for Healthcare Applications

Advanced Robotics Research, EarlyView.
Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir, Muhammad A. Khalid, Manish Chauhan, Pietro Valdastri, James H. Chandler   +4 more
wiley   +1 more source

Cryoablation for Small Renal Masses: Selection Criteria, Complications, and Functional and Oncologic Results

, 2016
Cryoablation (CA) is a minimally invasive modality with low complication rates, but its use in urology is relatively recent. To summarize available evidence for CA for small renal masses (SRMs) and to assess the selection criteria, complications, and ...
Atwell, Thomas D, Matin, Surena F., Zargar Shoshtari, Kamran, Janetschek, Gunther, Kaouk, Jihad H., de la Rosette, Jean J, Zargar-Shoshtari, Kamran, Polascik, Thomas J., Thompson, R Houston, de la Rosette, Jean J., Atwell, Thomas D., Polascik, Thomas J, Thompson, R. Houston, Cadeddu, Jeffrey A, Cadeddu, Jeffrey A., Zargar, Homayoun, Kaouk, Jihad H, Matin, Surena F   +17 more
core   +1 more source

Systematic review of perioperative and quality-of-life outcomes following surgical management of localised renal cancer [PDF]

, 2012
UCAN Cancer Charity (www.ucanhelp.org.uk) and MacMillan Cancer Charity (www.macmillan.org.uk) helped design and conduct the study.Peer ...
Hilvano-Cabungcal, Ana M., MacLennan, Steven, Griffiths, T. R. Leyshon, Griffiths, T.R. Leyshon, Lapitan, Marie C, Griffiths, TR Leyshon, UCAN Systematic Review Reference Group, Hilvano-Cabungcal, Ana M, MacLennan, Sara J, McClinton, Sam, MacLennan, Sara J., Lam, Thomas B. L., Ljungberg, Börje, N’Dow, James, Royle, Pamela, MacLennan, Graeme, Stewart, Fiona, Dahm, Philipp, Imamura, Mari, Canfield, Steven E, N'Dow, James, Royle, Pam, Lapitan, Marie C., Omar, Muhammad Imran, Lam, Thomas BL, Canfield, Steven E., Lam, Thomas B.L., Ljungberg, Börje,   +27 more
core   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source