Results 81 to 90 of about 3,186,814 (251)

The future of urology in Europe: an overview from the European association of urology

, 2001
INTRODUCTION: In order to be able to influence and monitor future developments for urologists, strategies should be promoted in advance to guarantee the future of the speciality and to accommodate the inevitable changes.
Martorana, G., Leisinger, H. J., Borowka, A., Kurth, K. H., Andersen, J. T., Vallancien, G., Vela Navarrete, R., Debruyne, F.   +7 more
core   +1 more source

Summary of European Association of Urology (EAU) Guidelines on Neuro-Urology

, 2016
CONTEXT Most patients with neuro-urological disorders require life-long medical care. The European Association of Urology (EAU) regularly updates guidelines for the diagnosis and treatment of these patients.
Castro Diaz, David, Pannek, Jürgen, Kessler, Thomas M, 't Hoen, Lisette, Groen, Jan, Schneider, Marc, Gross, Tobias, Blok, Bertil, Hamid, Rizwan, Del Popolo, Giulio, Karsenty, Gilles   +10 more
core   +1 more source

Robotic nurse duties in the urology operative room: 11 years of experience [PDF]

, 2017
The robotic nurse plays an essential role in a successful robotic surgery. As part of the robotic surgical team, the robotic nurse must demonstrate a high level of professional knowledge, and be an expert in robotic technology and dealing with robotic ...
최영득, 나군호, 장기돈
core   +1 more source

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

Advanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang, Song‐Zuo Xie, Yong‐Zhou Luo, Xin‐Pei Deng, Xi‐Rong Tan, Ze‐Geng Chen, Ling‐Xing Zeng, Gong Chen, Pei‐Rong Ding, Zhi‐Zhong Pan, Rong‐Xin Zhang   +10 more
wiley   +1 more source

Mechanism of Action of Botulinum Toxin A in Treatment of Functional Urological Disorders

Toxins, 2020
Intravesical botulinum toxin (BoNT) injection is effective in reducing urgency and urinary incontinence. It temporarily inhibits the detrusor muscle contraction by blocking the release of acetylcholine (Ach) from the preganglionic and postganglionic ...
Yu-Hua Lin, Bing-Juin Chiang, Chun-Hou Liao   +2 more
doaj   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

Advanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian, Shihang Pu, Zhipeng Xu, Yiheng Ding, Ling Jin, Baochao Li, Qi Li, Xiaohai Xi, Zengjun Wang, Jiajun Xing, Aiming Xu   +10 more
wiley   +1 more source

Impact of Lithotripsy Technology on Mini-PCNL Outcomes: A Comparative Study of Holmium and Thulium Laser

Journal of Urological Surgery
Objective: To evaluate outcomes of mini-percutaneous nephrolithotomy (PCNL) performed with holmium:YAG (Ho:YAG) versus thulium fiber laser (TFL). Materials and Methods: This retrospective study included adult patients who underwent mini-PCNL with either
Ersin Gökmen, Türker Altuntaş, Abdul Vahap Bakır, Kaan Derici, Günal Özgür, Tarık Emre Şener   +5 more
doaj   +1 more source

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

Advanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao, Xinhao Yuan, Shuai Liang, Kai Deng, Daqin Wu, Longhao Xu, Kun Zheng, Yi Lin, Peicong Cai, Haoran Zheng, Junyu Chen, Mingli Luo, Yan Chen, Xiong Chen, Chunhui Wang, Wenlong Zhong   +15 more
wiley   +1 more source

Can We Go beyond Pathology? The Prognostic Role of Risk Scoring Tools for Cancer-Specific Survival of Patients with Bladder Cancer Undergoing Radical Cystectomy

Biomedicines
Radical cystectomy (RC) remains a mainstay surgical treatment for non-metastatic muscle-invasive and BCG-unresponsive bladder cancer. Various perioperative scoring tools assess comorbidity burden, complication risks, and cancer-specific mortality (CSM ...
Aleksander Ślusarczyk, Rafał Wolański, Jerzy Miłow, Hanna Piekarczyk, Piotr Lipiński, Piotr Zapała, Grzegorz Niemczyk, Paweł Kurzyna, Andrzej Wróbel, Waldemar Różański, Piotr Radziszewski, Łukasz Zapała   +11 more
doaj   +1 more source