Results 81 to 90 of about 1,160,917 (294)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Functional Utility of Action in the Theoretical Perspective h. Spencer's Sociology
RUDN journal of Sociology, 2008 This paper analyses the concept of individual action in light of Herbert Spencer's social evolution model. Given the particularities of the historical period in which Spencer lived, several lines of theory held by Spencer's predecessors are derived that ...
J O Kryuchkova
doaj
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Influence of the mold inhibitor on productivity and functional activity of broiler chicken’s liver
Новые технологии, 2017 During the experiment broiler chickens were the object of the research. The purpose of the study was to study the effect of different doses of the Oxy-Nile mold inhibitor in rations with an increased content of B1 aflatoxin on the utility-beneficial ...
A. A. Baeva +3 more
doaj
Partial identification of willingness-to-pay using shape restrictions with an application to the value of a statistical life [PDF]
Economists often analyze cross-sectional data to estimate the value people implicit place on attributes of goods using hedonic methods. Usually strong enough assumptions are made on the functional form of utility to point identify individuals ...
Aaron Sojourner
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
mSystems, 2019 Functional metagenomics is a powerful tool for both the discovery and development of biocatalysts. This study presents the high-throughput functional screening of 22 large-insert fosmid libraries containing over 300,000 clones sourced from natural and ...
Zachary Armstrong +8 more
doaj +1 more source
Interpretation of Interpersonal Utility Comparisons: Positive, Normative or Descriptive [PDF]
, 1992 While interpersonal utility comparisons are indispensable to the determination of utility maxima, their interpretation as either normative or positive produces awkward conclusions.
Davis, John B.
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source