Results 81 to 90 of about 1,178,429 (294)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Non-parametric Test of Revealed Preference for Rational Behavior of Consumers: Urban Households [PDF]

open access: yesفصلنامه پژوهش‌های اقتصادی ایران, 2005
Non-parametric test of revealed preference identifies consumers' preferences by comparing their choices in different times. Unlike the parametric tests, non-parametric test means that no parameter is estimated and no functional form is imposed on the ...
Mohammad Ali Dehghan Dehnavi   +2 more
doaj  

Representations for optimal stopping under dynamic monetary utility functionals [PDF]

open access: yes
In this paper we consider the optimal stopping problem for general dynamic monetary utility functionals. Sufficient conditions for the Bellman principle and the existence of optimal stopping times are provided.
John Schoenmakers, Volker Krätschmer
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Robust Utility Maximization in a Stochastic Factor Model [PDF]

open access: yes
We give an explicit PDE characterization for the solution of a robust utility maximization problem in an incomplete market model, whose volatility, interest rate process, and long-term trend are driven by an external stochastic factor process. The robust
Alexander Schied   +1 more
core  

Sorghum Pan-Genome Explores the Functional Utility for Genomic-Assisted Breeding to Accelerate the Genetic Gain. [PDF]

open access: yesFront Plant Sci, 2021
Ruperao P   +13 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Functional Utility of Action in the Theoretical Perspective h. Spencer's Sociology

open access: yesRUDN journal of Sociology, 2008
This paper analyses the concept of individual action in light of Herbert Spencer's social evolution model. Given the particularities of the historical period in which Spencer lived, several lines of theory held by Spencer's predecessors are derived that ...
J O Kryuchkova
doaj  

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