Results 251 to 260 of about 11,051,876 (314)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Admission direct bilirubin and direct bilirubin-to-lymphocyte ratio as exploratory markers of early severity and in-hospital functional status in acute ischemic stroke. [PDF]

Front Stroke
Li Y, Zhang R, Luo Y, Gu Y.
europepmc   +1 more source

On the counting function for the alpha-values of a meromorphic function

Annales Academiae Scientiarum Fennicae Series A I Mathematica, 1976
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mechanism-Informed Pharmacotherapy Optimization and Deprescribing: A Redox-Mitochondrial Framework. [PDF]

Pharmacol Res Perspect
Martinc B.
europepmc   +1 more source

Integrated metagenomic and metabolomic analysis identifies severity-specific inflammatory and metabolic signatures in post-stroke depression. [PDF]

Gut Microbes
Chen W, Pan Y, Chen M, Zhou S, Liu X, Sun M, Yang Z, Zhi Y.   +7 more
europepmc   +1 more source

Prognostic value of the SPICE score for 1-year functional outcomes in patients with acute stroke requiring mechanical ventilation. [PDF]

BMJ Neurol Open
Mabiala T, Mazighi M, Collet M, Degos V, Duranteau J, Grégoire C, Sharshar T, Cortier D, Barhayiga B, Bula Bula M, Mananga Lelo G, Timsit JF, Sonneville R, de Montmollin E, SPICE investigators group.   +14 more
europepmc   +1 more source